The many connections of UFMylation with Alzheimer’s disease: a comprehensive review

The many connections of UFMylation with Alzheimer’s disease: a comprehensive review

Abstract Alzheimer’s disease (AD) is a complex neurodegenerative disorder that is characterized by the accumulation of pathologic tau and beta-amyloid proteins. UFMylation is an emerging ubiquitin-like post-translational modification that is crucial for healthy brain development. The UFM1 cascade wa...

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Bibliographic Details
Main Authors: Tingxiang Yan, Benjamin D. Clarkson, Zhenkun Lou, Wolfdieter Springer, Fabienne C. Fiesel
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Molecular Neurodegeneration
Online Access:https://doi.org/10.1186/s13024-025-00855-8
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