Noninvasive Evaluation of Portal Hypertension: Emerging Tools and Techniques
Portal hypertension is the main cause of complications in patients with cirrhosis. However, evaluating the development and progression of portal hypertension represents a challenge for clinicians. There has been considerable focus on the potential role of noninvasive markers of portal hypertension t...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | International Journal of Hepatology |
| Online Access: | http://dx.doi.org/10.1155/2012/691089 |
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| _version_ | 1849695303334100992 |
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| author | V. K. Snowdon N. Guha J. A. Fallowfield |
| author_facet | V. K. Snowdon N. Guha J. A. Fallowfield |
| author_sort | V. K. Snowdon |
| collection | DOAJ |
| description | Portal hypertension is the main cause of complications in patients with cirrhosis. However, evaluating the development and progression of portal hypertension represents a challenge for clinicians. There has been considerable focus on the potential role of noninvasive markers of portal hypertension that could be used to stratify patients with respect to the stage of portal hypertension and to monitor disease progression or treatment response in a longitudinal manner without having to undertake repeated invasive assessment. The pathogenesis of portal hypertension is increasingly understood and emerging knowledge of the vascular processes that underpin portal hypertension has paved the way for exploring novel biomarkers of vascular injury, angiogenesis, and endothelial dysfunction. In this paper we focus on the pathogenesis of portal hypertension and potential non-invasive biomarkers with particular emphasis on serum analytes. |
| format | Article |
| id | doaj-art-d785f138fe9047d786a922101c9fa4da |
| institution | DOAJ |
| issn | 2090-3448 2090-3456 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Hepatology |
| spelling | doaj-art-d785f138fe9047d786a922101c9fa4da2025-08-20T03:19:49ZengWileyInternational Journal of Hepatology2090-34482090-34562012-01-01201210.1155/2012/691089691089Noninvasive Evaluation of Portal Hypertension: Emerging Tools and TechniquesV. K. Snowdon0N. Guha1J. A. Fallowfield2MRC/Centre for Inflammation Research, QMRI, University of Edinburgh, Edinburgh EH16 4TJ, UKNottingham Digestive Diseases Centre, University of Nottingham, Nottingham NG7 2RD, UKMRC/Centre for Inflammation Research, QMRI, University of Edinburgh, Edinburgh EH16 4TJ, UKPortal hypertension is the main cause of complications in patients with cirrhosis. However, evaluating the development and progression of portal hypertension represents a challenge for clinicians. There has been considerable focus on the potential role of noninvasive markers of portal hypertension that could be used to stratify patients with respect to the stage of portal hypertension and to monitor disease progression or treatment response in a longitudinal manner without having to undertake repeated invasive assessment. The pathogenesis of portal hypertension is increasingly understood and emerging knowledge of the vascular processes that underpin portal hypertension has paved the way for exploring novel biomarkers of vascular injury, angiogenesis, and endothelial dysfunction. In this paper we focus on the pathogenesis of portal hypertension and potential non-invasive biomarkers with particular emphasis on serum analytes.http://dx.doi.org/10.1155/2012/691089 |
| spellingShingle | V. K. Snowdon N. Guha J. A. Fallowfield Noninvasive Evaluation of Portal Hypertension: Emerging Tools and Techniques International Journal of Hepatology |
| title | Noninvasive Evaluation of Portal Hypertension: Emerging Tools and Techniques |
| title_full | Noninvasive Evaluation of Portal Hypertension: Emerging Tools and Techniques |
| title_fullStr | Noninvasive Evaluation of Portal Hypertension: Emerging Tools and Techniques |
| title_full_unstemmed | Noninvasive Evaluation of Portal Hypertension: Emerging Tools and Techniques |
| title_short | Noninvasive Evaluation of Portal Hypertension: Emerging Tools and Techniques |
| title_sort | noninvasive evaluation of portal hypertension emerging tools and techniques |
| url | http://dx.doi.org/10.1155/2012/691089 |
| work_keys_str_mv | AT vksnowdon noninvasiveevaluationofportalhypertensionemergingtoolsandtechniques AT nguha noninvasiveevaluationofportalhypertensionemergingtoolsandtechniques AT jafallowfield noninvasiveevaluationofportalhypertensionemergingtoolsandtechniques |