Popliteal artery adventitial disease: A case report and understanding the pathophysiology and management

Popliteal artery adventitial disease: A case report and understanding the pathophysiology and management

Popliteal artery adventitial disease (PAAD) underlies a significant portion of vascular conditions of the lower extremities, often culminating in critical limb ischemia and warranting a greater clinical understanding for effective management. Characterized by the cystic degeneration of the adventiti...

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Main Authors: Dirk A. Le Roux, MBChB(Pret), FCS(SA), CVS(SA), Pradeep P. Mistry, MBChB(Pret), MMed Surgery(Pret), FCS(SA), CVS(SA), Lewis J. Levien, MBBCh, FCS(SA), PhD(MED), Hideaki Obara, MD, PhD, Rahul Agarwal, MBBS, DNB(General Surgery), DrNB(Vascular Surgery)
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:JVS-Vascular Insights
Subjects:
Cystic adventitial disease
Popliteal artery
Intermittent claudication
Adventitial cystic disease
Nonatherosclerotic vascular disease
Online Access:http://www.sciencedirect.com/science/article/pii/S2949912725000388
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Summary:Popliteal artery adventitial disease (PAAD) underlies a significant portion of vascular conditions of the lower extremities, often culminating in critical limb ischemia and warranting a greater clinical understanding for effective management. Characterized by the cystic degeneration of the adventitia of the popliteal artery, PAAD remains a challenging condition both in terms of diagnosis and treatment. This review seeks to explore the complex pathophysiology, diagnostic criteria, and current management strategies, as well as discussing emerging therapies and future outlook for patients with PAAD.
ISSN:2949-9127

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