Overexpression of the transcription factor Yap1 modifies intracellular redox conditions and enhances recombinant protein secretion
Oxidative folding of secretory proteins in the endoplasmic reticulum (ER) is a redox active process, which also impacts the redox conditions in the cytosol. As the transcription factor Yap1 is involved in the transcriptional response to oxidative stress, we investigate its role upon the production o...
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| Main Authors: | Marizela Delic, Alexandra B. Graf, Gunda Koellensperger, Christina Haberhauer-Troyer, Stephan Hann, Diethard Mattanovich, Brigitte Gasser |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Shared Science Publishers OG
2014-10-01
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| Series: | Microbial Cell |
| Subjects: | |
| Online Access: | http://microbialcell.com/researcharticles/overexpression-of-the-transcription-factor-yap1-modifies-intracellular-redox-conditions-and-enhances-recombinant-protein-secretion/ |
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