Intrasplenic metastasis of appendiceal low-grade mucinous neoplasm – A case report and review of the literature
Low-grade appendiceal mucinous neoplasms (LAMNs) may lead to pseudomyxoma peritonei and require specialized surgical therapy. By pathological definition, these tumor entities exhibit neither invasive growth nor develop systemic or lymph node metastases. We report the case of a 43-year-old female pre...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-06-01
|
| Series: | Current Problems in Cancer: Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S266662192500016X |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Low-grade appendiceal mucinous neoplasms (LAMNs) may lead to pseudomyxoma peritonei and require specialized surgical therapy. By pathological definition, these tumor entities exhibit neither invasive growth nor develop systemic or lymph node metastases. We report the case of a 43-year-old female presenting with a metachronous splenic metastasis of low-grade pseudomyxoma peritonei four years after surgical therapy. The patient was treated successfully via laparoscopic splenectomy. While the spleen itself is an extremely rare location for metastasizing colonic cancer, a LAMN metastasis in this location has not been previously described. A literature review of pseudomyxoma recurrence reveals that LAMNs might indeed recur in extraperitoneal locations, questioning their pathophysiological definition of non-metastasizing behavior. |
|---|---|
| ISSN: | 2666-6219 |