ID044 The Radioactive Seed localization For Impalpable Breast Cancer Conservative Surgery: Meta-Analysis
Introduction This study performs a meta-analysis of the Radioactive seed localization (RSL) technique efficiency for women who underwent impalpable breast lesions surgical localization, in comparison with Radio-guided occult lesion localization (ROLL) and wire-guided localization (WGL). Metho...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Instituto Nacional de Assistência Farmacêutica e Farmacoeconomia
2024-11-01
|
| Series: | Jornal de Assistência Farmacêutica e Farmacoeconomia |
| Subjects: | |
| Online Access: | https://ojs.jaff.org.br/ojs/index.php/jaff/article/view/873 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1846143235707109376 |
|---|---|
| author | Hortência de Jesus Ferreira Maria Elisa C. Martins Rostelato Carla Daruich de Souza Lorena Pozzo Martha Ribeiro |
| author_facet | Hortência de Jesus Ferreira Maria Elisa C. Martins Rostelato Carla Daruich de Souza Lorena Pozzo Martha Ribeiro |
| author_sort | Hortência de Jesus Ferreira |
| collection | DOAJ |
| description |
Introduction
This study performs a meta-analysis of the Radioactive seed localization (RSL) technique efficiency for women who underwent impalpable breast lesions surgical localization, in comparison with Radio-guided occult lesion localization (ROLL) and wire-guided localization (WGL).
Methods
The systematic research was performed in PubMed, Embase, LILACS, SciELO, and Web of Science with the key words. The selected studies went through a standard form of data extraction. The ROBINS-1 and ROB-2 tool was applied to analyze the bias risk and methodological quality. The review manager 5.4 software was used to perform the meta-analysis by the random effects analysis model.
Aftermath
In the comparison RSL x ROLL, the results found by the outcome were: positive surgical margins (RR 0.83, 95% CI 0.50 – 1.39, I2 39%; 763 patients), reoperation (RR 1.14, 95 % CI 0.75 – 1.74, I2 17%; 1550 patients), and recurrence (RR 0.50, 95% CI 0.29 – 0.87, I2 0; 939 patients). In the comparison RSL x WGL, the results found by the outcome were: positive surgical margins (RR 0.78, 95% CI 0.70 – 0.88, I2 37%; 15095 patients), reoperation (RR 0.71, 95% CI 0.61 – 0.84; I2 61%; 13884 patients), recurrence (RR 0.41, 95% CI 0.19 – 0.86; I2 0%; 1525 patients.
Discussions and conclusions
The results demonstrated that RSL is superior to WGL in surgical efficiency in the impalpable breast lesions intraoperative localization and is, at a minimum, equivalent to ROLL. RSL also presented promising results regarding the organization of services, proving to be superior to WGL and ROLL technologies, because a longer time between the lesion localization and the surgery allows greater flexibility in the scheduling of the radiology and surgery sectors, in addition to the possibility of the seed placement procedure taking place before neoadjuvant chemotherapy.
|
| format | Article |
| id | doaj-art-d780a57a84b6451fa81855815f7364ba |
| institution | Kabale University |
| issn | 2525-5010 2525-7323 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Instituto Nacional de Assistência Farmacêutica e Farmacoeconomia |
| record_format | Article |
| series | Jornal de Assistência Farmacêutica e Farmacoeconomia |
| spelling | doaj-art-d780a57a84b6451fa81855815f7364ba2024-12-02T19:58:00ZengInstituto Nacional de Assistência Farmacêutica e FarmacoeconomiaJornal de Assistência Farmacêutica e Farmacoeconomia2525-50102525-73232024-11-019s. 110.22563/2525-7323.2024.v9.s1.p.45ID044 The Radioactive Seed localization For Impalpable Breast Cancer Conservative Surgery: Meta-AnalysisHortência de Jesus FerreiraMaria Elisa C. Martins RostelatoCarla Daruich de SouzaLorena PozzoMartha Ribeiro Introduction This study performs a meta-analysis of the Radioactive seed localization (RSL) technique efficiency for women who underwent impalpable breast lesions surgical localization, in comparison with Radio-guided occult lesion localization (ROLL) and wire-guided localization (WGL). Methods The systematic research was performed in PubMed, Embase, LILACS, SciELO, and Web of Science with the key words. The selected studies went through a standard form of data extraction. The ROBINS-1 and ROB-2 tool was applied to analyze the bias risk and methodological quality. The review manager 5.4 software was used to perform the meta-analysis by the random effects analysis model. Aftermath In the comparison RSL x ROLL, the results found by the outcome were: positive surgical margins (RR 0.83, 95% CI 0.50 – 1.39, I2 39%; 763 patients), reoperation (RR 1.14, 95 % CI 0.75 – 1.74, I2 17%; 1550 patients), and recurrence (RR 0.50, 95% CI 0.29 – 0.87, I2 0; 939 patients). In the comparison RSL x WGL, the results found by the outcome were: positive surgical margins (RR 0.78, 95% CI 0.70 – 0.88, I2 37%; 15095 patients), reoperation (RR 0.71, 95% CI 0.61 – 0.84; I2 61%; 13884 patients), recurrence (RR 0.41, 95% CI 0.19 – 0.86; I2 0%; 1525 patients. Discussions and conclusions The results demonstrated that RSL is superior to WGL in surgical efficiency in the impalpable breast lesions intraoperative localization and is, at a minimum, equivalent to ROLL. RSL also presented promising results regarding the organization of services, proving to be superior to WGL and ROLL technologies, because a longer time between the lesion localization and the surgery allows greater flexibility in the scheduling of the radiology and surgery sectors, in addition to the possibility of the seed placement procedure taking place before neoadjuvant chemotherapy. https://ojs.jaff.org.br/ojs/index.php/jaff/article/view/873Meta-analysisRadioactive seedIntraoperative localizationImpalpable breast cancerConservative surgery |
| spellingShingle | Hortência de Jesus Ferreira Maria Elisa C. Martins Rostelato Carla Daruich de Souza Lorena Pozzo Martha Ribeiro ID044 The Radioactive Seed localization For Impalpable Breast Cancer Conservative Surgery: Meta-Analysis Jornal de Assistência Farmacêutica e Farmacoeconomia Meta-analysis Radioactive seed Intraoperative localization Impalpable breast cancer Conservative surgery |
| title | ID044 The Radioactive Seed localization For Impalpable Breast Cancer Conservative Surgery: Meta-Analysis |
| title_full | ID044 The Radioactive Seed localization For Impalpable Breast Cancer Conservative Surgery: Meta-Analysis |
| title_fullStr | ID044 The Radioactive Seed localization For Impalpable Breast Cancer Conservative Surgery: Meta-Analysis |
| title_full_unstemmed | ID044 The Radioactive Seed localization For Impalpable Breast Cancer Conservative Surgery: Meta-Analysis |
| title_short | ID044 The Radioactive Seed localization For Impalpable Breast Cancer Conservative Surgery: Meta-Analysis |
| title_sort | id044 the radioactive seed localization for impalpable breast cancer conservative surgery meta analysis |
| topic | Meta-analysis Radioactive seed Intraoperative localization Impalpable breast cancer Conservative surgery |
| url | https://ojs.jaff.org.br/ojs/index.php/jaff/article/view/873 |
| work_keys_str_mv | AT hortenciadejesusferreira id044theradioactiveseedlocalizationforimpalpablebreastcancerconservativesurgerymetaanalysis AT mariaelisacmartinsrostelato id044theradioactiveseedlocalizationforimpalpablebreastcancerconservativesurgerymetaanalysis AT carladaruichdesouza id044theradioactiveseedlocalizationforimpalpablebreastcancerconservativesurgerymetaanalysis AT lorenapozzo id044theradioactiveseedlocalizationforimpalpablebreastcancerconservativesurgerymetaanalysis AT martharibeiro id044theradioactiveseedlocalizationforimpalpablebreastcancerconservativesurgerymetaanalysis |