Microbiological Justification of the Germicide Selection for the Treatment of Salmonellosis in Children

The article presents the data on determination of sensitivity of Salmonella strains in vitro by the method of serial dilutions in broth with the determination of the minimum inhibitory concentrations (MIC) to antimicrobial agents in accordance with the 2015 EUCAST (European Committee on Antimicrobia...

Full description

Saved in:
Bibliographic Details
Main Authors: L. P. Zharkova, N. N. Smolyankin, A. I. Grekova, S. N. Kozlov
Format: Article
Language:Russian
Published: LLC "Publishing House OKI" 2020-05-01
Series:Антибиотики и Химиотерапия
Subjects:
Online Access:https://www.antibiotics-chemotherapy.ru/jour/article/view/38
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849389148402614272
author L. P. Zharkova
N. N. Smolyankin
A. I. Grekova
S. N. Kozlov
author_facet L. P. Zharkova
N. N. Smolyankin
A. I. Grekova
S. N. Kozlov
author_sort L. P. Zharkova
collection DOAJ
description The article presents the data on determination of sensitivity of Salmonella strains in vitro by the method of serial dilutions in broth with the determination of the minimum inhibitory concentrations (MIC) to antimicrobial agents in accordance with the 2015 EUCAST (European Committee on Antimicrobial Susceptibility Testing European Committee for determination of sensitivity to antimicrobial agents) criteria and national clinical guidelines. The study demonstrated a high pharmacodynamic activity of the III generation cephalosporins (Cefotaxime, cefepime), azithromycin, co-trimoxazole and the presence of Salmonella with resistance to ciprofloxacin (24.3%).
format Article
id doaj-art-d77e029a4c9047cd8a2d1d9ebe9fbb31
institution Kabale University
issn 0235-2990
language Russian
publishDate 2020-05-01
publisher LLC "Publishing House OKI"
record_format Article
series Антибиотики и Химиотерапия
spelling doaj-art-d77e029a4c9047cd8a2d1d9ebe9fbb312025-08-20T03:42:02ZrusLLC "Publishing House OKI"Антибиотики и Химиотерапия0235-29902020-05-01627-8303537Microbiological Justification of the Germicide Selection for the Treatment of Salmonellosis in ChildrenL. P. Zharkova0N. N. Smolyankin1A. I. Grekova2S. N. Kozlov3Smolensk State Medical UniversitySmolensk State Medical UniversitySmolensk State Medical UniversitySmolensk State Medical UniversityThe article presents the data on determination of sensitivity of Salmonella strains in vitro by the method of serial dilutions in broth with the determination of the minimum inhibitory concentrations (MIC) to antimicrobial agents in accordance with the 2015 EUCAST (European Committee on Antimicrobial Susceptibility Testing European Committee for determination of sensitivity to antimicrobial agents) criteria and national clinical guidelines. The study demonstrated a high pharmacodynamic activity of the III generation cephalosporins (Cefotaxime, cefepime), azithromycin, co-trimoxazole and the presence of Salmonella with resistance to ciprofloxacin (24.3%).https://www.antibiotics-chemotherapy.ru/jour/article/view/38salmonella strainsmic of antibiotics (iii generation cephalosporinsazithromycinciprofloxacinco-trimoxazole)children
spellingShingle L. P. Zharkova
N. N. Smolyankin
A. I. Grekova
S. N. Kozlov
Microbiological Justification of the Germicide Selection for the Treatment of Salmonellosis in Children
Антибиотики и Химиотерапия
salmonella strains
mic of antibiotics (iii generation cephalosporins
azithromycin
ciprofloxacin
co-trimoxazole)
children
title Microbiological Justification of the Germicide Selection for the Treatment of Salmonellosis in Children
title_full Microbiological Justification of the Germicide Selection for the Treatment of Salmonellosis in Children
title_fullStr Microbiological Justification of the Germicide Selection for the Treatment of Salmonellosis in Children
title_full_unstemmed Microbiological Justification of the Germicide Selection for the Treatment of Salmonellosis in Children
title_short Microbiological Justification of the Germicide Selection for the Treatment of Salmonellosis in Children
title_sort microbiological justification of the germicide selection for the treatment of salmonellosis in children
topic salmonella strains
mic of antibiotics (iii generation cephalosporins
azithromycin
ciprofloxacin
co-trimoxazole)
children
url https://www.antibiotics-chemotherapy.ru/jour/article/view/38
work_keys_str_mv AT lpzharkova microbiologicaljustificationofthegermicideselectionforthetreatmentofsalmonellosisinchildren
AT nnsmolyankin microbiologicaljustificationofthegermicideselectionforthetreatmentofsalmonellosisinchildren
AT aigrekova microbiologicaljustificationofthegermicideselectionforthetreatmentofsalmonellosisinchildren
AT snkozlov microbiologicaljustificationofthegermicideselectionforthetreatmentofsalmonellosisinchildren