Adsorption and Vibrational Study of Folic Acid on Gold Nanopillar Structures Using Surface-enhanced Raman Scattering Spectroscopy

This paper presents a study of adsorption and vibrational features of folic acid, using surface-enhanced Raman scattering (SERS). A gold-capped silicon nanopillar (Au NP) with a height of 600 nm and a width of 120 nm was utilized to study the vibrational features of FA molecules adsorbed on the nano...

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Main Authors: John J. Castillo, Tomas Rindzevicius, Ciro E. Rozo, Anja Boisen
Format: Article
Language:English
Published: Wiley 2015-10-01
Series:Nanomaterials and Nanotechnology
Subjects:
Online Access:http://www.intechopen.com/journals/nanomaterials_and_nanotechnology/adsorption-and-vibrational-study-of-folic-acid-on-gold-nanopillar-structures-using-surface-enhanced-
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author John J. Castillo
Tomas Rindzevicius
Ciro E. Rozo
Anja Boisen
author_facet John J. Castillo
Tomas Rindzevicius
Ciro E. Rozo
Anja Boisen
author_sort John J. Castillo
collection DOAJ
description This paper presents a study of adsorption and vibrational features of folic acid, using surface-enhanced Raman scattering (SERS). A gold-capped silicon nanopillar (Au NP) with a height of 600 nm and a width of 120 nm was utilized to study the vibrational features of FA molecules adsorbed on the nanopillars within the high electromag‐ netic field areas. The adsorption behaviour of folic acid and the band assignment of the main vibrations together with the optimized geometry of folic acid and folic acid in the presence of a cluster of 10 gold atoms were assessed using the density functional theory (B3LYP(6-31G(d))) and the scalar relativistic effective core potential with a double-zeta basis set (LANL2DZ). The vibrations obtained from the solid-state folic acid and the folic acid on a gold cluster were in accordance with those observed experimentally. The analysis of the main vibrations indicated that the interac‐ tion of folic acid with the Au NP occurred primarily through the nitrogen atoms, from their pteridine ring. Finally, the obtained adsorption isotherm for folic acid was deduced from the analysis of the SERS spectra and it followed a negative cooperative binding model.
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spelling doaj-art-d776ff5e6d3c44598688ee663b6bfc892025-08-20T02:20:09ZengWileyNanomaterials and Nanotechnology1847-98042015-10-01529http://dx.doi.org/10.5772/6160649347Adsorption and Vibrational Study of Folic Acid on Gold Nanopillar Structures Using Surface-enhanced Raman Scattering SpectroscopyJohn J. CastilloTomas RindzeviciusCiro E. RozoAnja BoisenThis paper presents a study of adsorption and vibrational features of folic acid, using surface-enhanced Raman scattering (SERS). A gold-capped silicon nanopillar (Au NP) with a height of 600 nm and a width of 120 nm was utilized to study the vibrational features of FA molecules adsorbed on the nanopillars within the high electromag‐ netic field areas. The adsorption behaviour of folic acid and the band assignment of the main vibrations together with the optimized geometry of folic acid and folic acid in the presence of a cluster of 10 gold atoms were assessed using the density functional theory (B3LYP(6-31G(d))) and the scalar relativistic effective core potential with a double-zeta basis set (LANL2DZ). The vibrations obtained from the solid-state folic acid and the folic acid on a gold cluster were in accordance with those observed experimentally. The analysis of the main vibrations indicated that the interac‐ tion of folic acid with the Au NP occurred primarily through the nitrogen atoms, from their pteridine ring. Finally, the obtained adsorption isotherm for folic acid was deduced from the analysis of the SERS spectra and it followed a negative cooperative binding model.http://www.intechopen.com/journals/nanomaterials_and_nanotechnology/adsorption-and-vibrational-study-of-folic-acid-on-gold-nanopillar-structures-using-surface-enhanced-Gold NanopillarsSERSFolic Acid
spellingShingle John J. Castillo
Tomas Rindzevicius
Ciro E. Rozo
Anja Boisen
Adsorption and Vibrational Study of Folic Acid on Gold Nanopillar Structures Using Surface-enhanced Raman Scattering Spectroscopy
Nanomaterials and Nanotechnology
Gold Nanopillars
SERS
Folic Acid
title Adsorption and Vibrational Study of Folic Acid on Gold Nanopillar Structures Using Surface-enhanced Raman Scattering Spectroscopy
title_full Adsorption and Vibrational Study of Folic Acid on Gold Nanopillar Structures Using Surface-enhanced Raman Scattering Spectroscopy
title_fullStr Adsorption and Vibrational Study of Folic Acid on Gold Nanopillar Structures Using Surface-enhanced Raman Scattering Spectroscopy
title_full_unstemmed Adsorption and Vibrational Study of Folic Acid on Gold Nanopillar Structures Using Surface-enhanced Raman Scattering Spectroscopy
title_short Adsorption and Vibrational Study of Folic Acid on Gold Nanopillar Structures Using Surface-enhanced Raman Scattering Spectroscopy
title_sort adsorption and vibrational study of folic acid on gold nanopillar structures using surface enhanced raman scattering spectroscopy
topic Gold Nanopillars
SERS
Folic Acid
url http://www.intechopen.com/journals/nanomaterials_and_nanotechnology/adsorption-and-vibrational-study-of-folic-acid-on-gold-nanopillar-structures-using-surface-enhanced-
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AT ciroerozo adsorptionandvibrationalstudyoffolicacidongoldnanopillarstructuresusingsurfaceenhancedramanscatteringspectroscopy
AT anjaboisen adsorptionandvibrationalstudyoffolicacidongoldnanopillarstructuresusingsurfaceenhancedramanscatteringspectroscopy