Pharmacokinetic variability of 20(S)-protopanaxadiol-type ginsenosides Rb1, rd, and compound K from Korean red ginseng in experimental rodents

Pharmacokinetic variability of 20(S)-protopanaxadiol-type ginsenosides Rb1, rd, and compound K from Korean red ginseng in experimental rodents

Abstract Korean red ginseng (KRG, Panax ginseng C.A. Meyer) contains ginsenosides, which are metabolized into active metabolites with various pharmacological effects. This study assessed the in vivo exposure and accumulation of ginsenosides following single and repeated administration of KRG and its...

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Bibliographic Details
Main Authors: Ji-Soo Jeong, Jeong-Won Kim, Jin-Hwa Kim, Chang-Yeop Kim, Eun-Hye Chung, So-Young Boo, Mario Giorgi, Je-Won Ko, Tae-Won Kim
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Pharmacokinetics
Korean red ginseng
Ginsenoside
Compound k
Metabolic conversion
Online Access:https://doi.org/10.1038/s41598-025-13873-9
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