Morbimortality related to the treatment of the soft tissue sarcomas
Objective: To characterize patients with soft tissue sarcoma in their demographic, clinical, histopathological and treatment aspects, treatment toxicity, and postoperative complications occurring within 30 days of the first surgery. Methods: A retrospective cohort study with clinical data...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Thieme Revinter Publicações Ltda.
2020-01-01
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| Series: | Brazilian Journal of Oncology |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.5935/2526-8732.20200014 |
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| Summary: | Objective: To characterize patients with soft tissue sarcoma in their demographic, clinical, histopathological and treatment aspects, treatment toxicity, and postoperative complications occurring within 30 days of the first surgery. Methods: A retrospective cohort study with clinical data collection and referring to the treatment of patients with soft tissue sarcomas, obtained through patients records from January to December 2017. The main focus was the analysis of the data of acute morbimortality related to the patient and tumor, graded by CTCAE (Common Terminology Criteria for Adverse Events). For this, we use data from a single tertiary institution leading the treatment of cancer in Brazil. Results: There was a higher prevalence of localization of sarcomas in extremities. The initial treatment is usually total excision, the number of postoperative complications was high (29.3%), such as signs of infection, surgical wound dehiscence, seroma formation, among others. Morbidities requiring hospitalization within 30 days of initiation of treatment were observed in 6 patients (9.84%), the majority with treatment or disease-related cause. The occurrence of death up to 30 postoperative days or up to 3 cycles of systemic therapy was not observed. Conclusion: Despite a high morbidity rate, much of it was mild and not associated with mortality. The study of the sarcoma-bearing population makes it possible to create realistic treatment strategies, as well as the use of the database for future research. |
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| ISSN: | 2526-8732 |