Etiopathogenetic features of recurrent aphthous stomatitis: modern approaches to prevention and treatment

Recurrent aphthous stomatitis (RAS) is an inflammatory disease of the oral mucosa, which has a chronic course with periods of remission and exacerbations. RAS requires adequate diagnosis for the purposes of properly treating. The study on RAS remains relevant over many years and continues to be a...

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Main Authors: K. S. Hanchev, O. O. Kokar
Format: Article
Language:English
Published: Zaporizhzhia State Medical and Pharmaceutical University 2023-07-01
Series:Zaporožskij Medicinskij Žurnal
Subjects:
Online Access:http://zmj.zsmu.edu.ua/article/view/274414/279343
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author K. S. Hanchev
O. O. Kokar
author_facet K. S. Hanchev
O. O. Kokar
author_sort K. S. Hanchev
collection DOAJ
description Recurrent aphthous stomatitis (RAS) is an inflammatory disease of the oral mucosa, which has a chronic course with periods of remission and exacerbations. RAS requires adequate diagnosis for the purposes of properly treating. The study on RAS remains relevant over many years and continues to be a priority in modern dentistry. The aim of the work is to analyze the information in the professional literature on pathogenetic variants of RAS and approaches to its treatment and prevention. Despite the variety of studies, the etiology and pathogenesis of the disease remain the subject of numerous discussions. This article provides a review of current research on the main etiopathogenetic mechanisms of the disease development and progression, specifies current recommendations for therapeutic approaches to treatment and prevention. Conclusions. To date, there is no definitive therapeutic tactic for recurrent aphthous stomatitis, so it is advisable to systematize and study methods for the prevention and treatment of this pathology, including pain relief, acceleration of ulcer healing and reduction of its episode frequency and severity. Considering the etiopathogenetic variant of the disease development (metabolic disorders, stress, allergies, etc.), preventive measures should be comprehensive and include oral hygiene, a sparing diet, multivitamin and micro-, macroelement complexes, etc.
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spelling doaj-art-d76ed74af58943ff9a3c53e7083bf9412025-08-20T02:19:34ZengZaporizhzhia State Medical and Pharmaceutical UniversityZaporožskij Medicinskij Žurnal2306-41452310-12102023-07-0125436036410.14739/2310-1210.2023.4.274414Etiopathogenetic features of recurrent aphthous stomatitis: modern approaches to prevention and treatmentK. S. Hanchev0https://orcid.org/0000-0002-5878-7980O. O. Kokar1https://orcid.org/0000-0001-7195-6999Zaporizhzhia State Medical and Pharmaceutical University, UkraineZaporizhzhia State Medical and Pharmaceutical University, UkraineRecurrent aphthous stomatitis (RAS) is an inflammatory disease of the oral mucosa, which has a chronic course with periods of remission and exacerbations. RAS requires adequate diagnosis for the purposes of properly treating. The study on RAS remains relevant over many years and continues to be a priority in modern dentistry. The aim of the work is to analyze the information in the professional literature on pathogenetic variants of RAS and approaches to its treatment and prevention. Despite the variety of studies, the etiology and pathogenesis of the disease remain the subject of numerous discussions. This article provides a review of current research on the main etiopathogenetic mechanisms of the disease development and progression, specifies current recommendations for therapeutic approaches to treatment and prevention. Conclusions. To date, there is no definitive therapeutic tactic for recurrent aphthous stomatitis, so it is advisable to systematize and study methods for the prevention and treatment of this pathology, including pain relief, acceleration of ulcer healing and reduction of its episode frequency and severity. Considering the etiopathogenetic variant of the disease development (metabolic disorders, stress, allergies, etc.), preventive measures should be comprehensive and include oral hygiene, a sparing diet, multivitamin and micro-, macroelement complexes, etc.http://zmj.zsmu.edu.ua/article/view/274414/279343aphthous stomatitisrecurrencetreatmentdental prophylaxisaphthaemouth ulcers
spellingShingle K. S. Hanchev
O. O. Kokar
Etiopathogenetic features of recurrent aphthous stomatitis: modern approaches to prevention and treatment
Zaporožskij Medicinskij Žurnal
aphthous stomatitis
recurrence
treatment
dental prophylaxis
aphthae
mouth ulcers
title Etiopathogenetic features of recurrent aphthous stomatitis: modern approaches to prevention and treatment
title_full Etiopathogenetic features of recurrent aphthous stomatitis: modern approaches to prevention and treatment
title_fullStr Etiopathogenetic features of recurrent aphthous stomatitis: modern approaches to prevention and treatment
title_full_unstemmed Etiopathogenetic features of recurrent aphthous stomatitis: modern approaches to prevention and treatment
title_short Etiopathogenetic features of recurrent aphthous stomatitis: modern approaches to prevention and treatment
title_sort etiopathogenetic features of recurrent aphthous stomatitis modern approaches to prevention and treatment
topic aphthous stomatitis
recurrence
treatment
dental prophylaxis
aphthae
mouth ulcers
url http://zmj.zsmu.edu.ua/article/view/274414/279343
work_keys_str_mv AT kshanchev etiopathogeneticfeaturesofrecurrentaphthousstomatitismodernapproachestopreventionandtreatment
AT ookokar etiopathogeneticfeaturesofrecurrentaphthousstomatitismodernapproachestopreventionandtreatment