The outbreak of the new coronavirus infection in pediatric TB department
The objective: to analyze the course of the new coronavirus infection (COVID-19) in children with active respiratory tuberculosis. Subjects and methods. The article describes results of retrospective analysis of the course of the new coronavirus infection in 25 children (3-12 years old) with active...
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2020-11-01
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| Series: | Туберкулез и болезни лёгких |
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| Online Access: | https://www.tibl-journal.com/jour/article/view/1467 |
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| author | M. F. Gubkina I. Yu. Petrakova N. V. Yukhimenko S. S. Sterlikova Yu. Yu. Khokhlova R. B. Аmansakhedov |
| author_facet | M. F. Gubkina I. Yu. Petrakova N. V. Yukhimenko S. S. Sterlikova Yu. Yu. Khokhlova R. B. Аmansakhedov |
| author_sort | M. F. Gubkina |
| collection | DOAJ |
| description | The objective: to analyze the course of the new coronavirus infection (COVID-19) in children with active respiratory tuberculosis. Subjects and methods. The article describes results of retrospective analysis of the course of the new coronavirus infection in 25 children (3-12 years old) with active respiratory tuberculosis during the outbreak of COVID-19 in an in-patient TB unit.Results. 24 (96%) persons got infected after the close exposure to the coronavirus infection, and 1 (4%) child didn't get infected. The diagnosis was verified by polymerase chain reaction (detection of RNK of SARS-CoV-2) in 33.3%, by enzyme immunoassay (detection of IgG antibodies to SARS-CoV-2 in 1 month after quarantine removal) in 100%. 58.3% of children with respiratory tuberculosis (14 people) infected with coronavirus infection had minimal respiratory symptoms, that did not differ from signs of other respiratory viral infections; clinical manifestations of the disease were completely absent in 41.7% (10) patients. Coronavirus pneumonia was diagnosed in 4 (16.7%) children who suffered from COVID-19, they had no clinical signs of lower respiratory tract disorders and no body temperature increase; 3 patients had no signs of respiratory viral infection; in all cases, the lung damage detected by computed tomography didn't exceed 10%. In 2 months after the removal of quarantine, no IgG antibodies to SARS-CoV-2 were detected in 2 out of 10 examined children (20.0%), thus there was a chance for re-infection. No mutual aggravating effect of coronavirus infection and tuberculosis was revealed in their combination over the entire observation period (4 months). |
| format | Article |
| id | doaj-art-d76e01387b254ed3aec726ec5b8c9e7d |
| institution | DOAJ |
| issn | 2075-1230 2542-1506 |
| language | Russian |
| publishDate | 2020-11-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Туберкулез и болезни лёгких |
| spelling | doaj-art-d76e01387b254ed3aec726ec5b8c9e7d2025-08-20T03:02:41ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062020-11-01981061010.21292/2075-1230-2020-98-10-6-101465The outbreak of the new coronavirus infection in pediatric TB departmentM. F. Gubkina0I. Yu. Petrakova1N. V. Yukhimenko2S. S. Sterlikova3Yu. Yu. Khokhlova4R. B. Аmansakhedov5Central Tuberculosis Research Institute, Moscow; Pirogov Russian National Research Medical UniversityCentral Tuberculosis Research InstituteCentral Tuberculosis Research InstituteCentral Tuberculosis Research InstituteCentral Tuberculosis Research InstituteCentral Tuberculosis Research InstituteThe objective: to analyze the course of the new coronavirus infection (COVID-19) in children with active respiratory tuberculosis. Subjects and methods. The article describes results of retrospective analysis of the course of the new coronavirus infection in 25 children (3-12 years old) with active respiratory tuberculosis during the outbreak of COVID-19 in an in-patient TB unit.Results. 24 (96%) persons got infected after the close exposure to the coronavirus infection, and 1 (4%) child didn't get infected. The diagnosis was verified by polymerase chain reaction (detection of RNK of SARS-CoV-2) in 33.3%, by enzyme immunoassay (detection of IgG antibodies to SARS-CoV-2 in 1 month after quarantine removal) in 100%. 58.3% of children with respiratory tuberculosis (14 people) infected with coronavirus infection had minimal respiratory symptoms, that did not differ from signs of other respiratory viral infections; clinical manifestations of the disease were completely absent in 41.7% (10) patients. Coronavirus pneumonia was diagnosed in 4 (16.7%) children who suffered from COVID-19, they had no clinical signs of lower respiratory tract disorders and no body temperature increase; 3 patients had no signs of respiratory viral infection; in all cases, the lung damage detected by computed tomography didn't exceed 10%. In 2 months after the removal of quarantine, no IgG antibodies to SARS-CoV-2 were detected in 2 out of 10 examined children (20.0%), thus there was a chance for re-infection. No mutual aggravating effect of coronavirus infection and tuberculosis was revealed in their combination over the entire observation period (4 months).https://www.tibl-journal.com/jour/article/view/1467coronavirus infection (covid-19)respiratory tuberculosischildren |
| spellingShingle | M. F. Gubkina I. Yu. Petrakova N. V. Yukhimenko S. S. Sterlikova Yu. Yu. Khokhlova R. B. Аmansakhedov The outbreak of the new coronavirus infection in pediatric TB department Туберкулез и болезни лёгких coronavirus infection (covid-19) respiratory tuberculosis children |
| title | The outbreak of the new coronavirus infection in pediatric TB department |
| title_full | The outbreak of the new coronavirus infection in pediatric TB department |
| title_fullStr | The outbreak of the new coronavirus infection in pediatric TB department |
| title_full_unstemmed | The outbreak of the new coronavirus infection in pediatric TB department |
| title_short | The outbreak of the new coronavirus infection in pediatric TB department |
| title_sort | outbreak of the new coronavirus infection in pediatric tb department |
| topic | coronavirus infection (covid-19) respiratory tuberculosis children |
| url | https://www.tibl-journal.com/jour/article/view/1467 |
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