Disruption of DMD gene leads to altered calcium homeostasis and metabolic shift impacting gastric Cancer cell proliferation and migration

Disruption of DMD gene leads to altered calcium homeostasis and metabolic shift impacting gastric Cancer cell proliferation and migration

Abstract Background DMD gene has been implicated in the progression and development of several tumors, but its specific contribution to gastric cancer (GC) has not been fully elucidated. Methods We validated DMD gene expression levels in the TIMER2.0 database and human gastric cancer tissue microarr...

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Bibliographic Details
Main Authors: Xiaodong Zou, Tong Wu, Tao Su, Hui Xiao, Chuyan Ni, Lijuan Hu, Wenchu Lin, Weilin Chen, Richard D Ye, Jianjiao Lin, Li Xiang
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Cancer Cell International
Subjects:
Gastric cancer
DMD gene
Calcium homeostasis
Mitochondrial dysfunction
Glycolysis
Online Access:https://doi.org/10.1186/s12935-025-03829-4
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