Depression among people living with tuberculosis and tuberculosis/HIV coinfection in Ukraine: a cross-sectional study
Background Depressive disorders are associated with poor treatment outcomes, physical health, and quality of life among people living with TB (PLWTB) and TB/HIV (PLWTBHIV). Data on depression among PLWTB/HIV are limited in Ukraine. Objectives This cross-sectional study aimed to examine depression ri...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2025-12-01
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| Series: | Global Health Action |
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| Online Access: | http://dx.doi.org/10.1080/16549716.2024.2448894 |
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| author | Anna Salnikova Olena Makarenko Yuliia Sereda Tetiana Kiriazova Karsten Lunze Jack DeHovitz Danielle C. Ompad |
| author_facet | Anna Salnikova Olena Makarenko Yuliia Sereda Tetiana Kiriazova Karsten Lunze Jack DeHovitz Danielle C. Ompad |
| author_sort | Anna Salnikova |
| collection | DOAJ |
| description | Background Depressive disorders are associated with poor treatment outcomes, physical health, and quality of life among people living with TB (PLWTB) and TB/HIV (PLWTBHIV). Data on depression among PLWTB/HIV are limited in Ukraine. Objectives This cross-sectional study aimed to examine depression risk and its correlates and describe the willingness to seek depression treatment among PLWTB/HIV in Ukraine. Methods This secondary analysis included patients with and without HIV who initiated TB treatment within 30 days in two tertiary hospitals in Kyiv and Odesa. A survey was conducted from February 2021 to October 2022 and reviewed patients’ health records. We used the Center for Epidemiological Studies-Depression Scale (CES-D) to indicate risk for clinical depression. Factors associated with depressive symptoms were identified using logistic regression. Results The sample included 209 participants (n = 100 with TB; n = 109 with TB/HIV). The mean age of participants was 43 (SD = 11) years; 66% of sample identified as male. Approximately 28% of participants were at risk for clinical depression; of whom 66% were willing to seek therapeutic or medical help. HIV coinfection (adjusted odds ratio [aOR] = 2.95, 95% confidence interval [CI]: 1.46,6.20), past 30 days illicit drug use (aOR = 3.57, 95% CI = 1.18,11.60), TB stigma (moderate stigma aOR = 7.40, 95% CI = 2.22,34.1; high stigma aOR = 15.50, 95% CI = 4.52,73.20), and unemployment status (aOR = 2.25, 95% CI = 1.12,4.60) were significantly associated with the odds of depressive symptoms among PLWTB. Conclusion Findings support integration of a brief depression screening tool into routine clinical care of PLWTB/HIV and highlight the importance of linking TB/HIV care with mental health services. |
| format | Article |
| id | doaj-art-d76cbfceb08a4700aaecbcde9a9226d7 |
| institution | DOAJ |
| issn | 1654-9880 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Global Health Action |
| spelling | doaj-art-d76cbfceb08a4700aaecbcde9a9226d72025-08-20T02:45:42ZengTaylor & Francis GroupGlobal Health Action1654-98802025-12-0118110.1080/16549716.2024.24488942448894Depression among people living with tuberculosis and tuberculosis/HIV coinfection in Ukraine: a cross-sectional studyAnna Salnikova0Olena Makarenko1Yuliia Sereda2Tetiana Kiriazova3Karsten Lunze4Jack DeHovitz5Danielle C. Ompad6Ukrainian Institute on Public Health PolicyUkrainian Institute on Public Health PolicyUkrainian Institute on Public Health PolicyUkrainian Institute on Public Health PolicyBoston Medical CenterSUNY Downstate Health Sciences UniversityNew York University School of Global Public HealthBackground Depressive disorders are associated with poor treatment outcomes, physical health, and quality of life among people living with TB (PLWTB) and TB/HIV (PLWTBHIV). Data on depression among PLWTB/HIV are limited in Ukraine. Objectives This cross-sectional study aimed to examine depression risk and its correlates and describe the willingness to seek depression treatment among PLWTB/HIV in Ukraine. Methods This secondary analysis included patients with and without HIV who initiated TB treatment within 30 days in two tertiary hospitals in Kyiv and Odesa. A survey was conducted from February 2021 to October 2022 and reviewed patients’ health records. We used the Center for Epidemiological Studies-Depression Scale (CES-D) to indicate risk for clinical depression. Factors associated with depressive symptoms were identified using logistic regression. Results The sample included 209 participants (n = 100 with TB; n = 109 with TB/HIV). The mean age of participants was 43 (SD = 11) years; 66% of sample identified as male. Approximately 28% of participants were at risk for clinical depression; of whom 66% were willing to seek therapeutic or medical help. HIV coinfection (adjusted odds ratio [aOR] = 2.95, 95% confidence interval [CI]: 1.46,6.20), past 30 days illicit drug use (aOR = 3.57, 95% CI = 1.18,11.60), TB stigma (moderate stigma aOR = 7.40, 95% CI = 2.22,34.1; high stigma aOR = 15.50, 95% CI = 4.52,73.20), and unemployment status (aOR = 2.25, 95% CI = 1.12,4.60) were significantly associated with the odds of depressive symptoms among PLWTB. Conclusion Findings support integration of a brief depression screening tool into routine clinical care of PLWTB/HIV and highlight the importance of linking TB/HIV care with mental health services.http://dx.doi.org/10.1080/16549716.2024.2448894depressiontuberculosishivmental healthukraine |
| spellingShingle | Anna Salnikova Olena Makarenko Yuliia Sereda Tetiana Kiriazova Karsten Lunze Jack DeHovitz Danielle C. Ompad Depression among people living with tuberculosis and tuberculosis/HIV coinfection in Ukraine: a cross-sectional study Global Health Action depression tuberculosis hiv mental health ukraine |
| title | Depression among people living with tuberculosis and tuberculosis/HIV coinfection in Ukraine: a cross-sectional study |
| title_full | Depression among people living with tuberculosis and tuberculosis/HIV coinfection in Ukraine: a cross-sectional study |
| title_fullStr | Depression among people living with tuberculosis and tuberculosis/HIV coinfection in Ukraine: a cross-sectional study |
| title_full_unstemmed | Depression among people living with tuberculosis and tuberculosis/HIV coinfection in Ukraine: a cross-sectional study |
| title_short | Depression among people living with tuberculosis and tuberculosis/HIV coinfection in Ukraine: a cross-sectional study |
| title_sort | depression among people living with tuberculosis and tuberculosis hiv coinfection in ukraine a cross sectional study |
| topic | depression tuberculosis hiv mental health ukraine |
| url | http://dx.doi.org/10.1080/16549716.2024.2448894 |
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