WNT11 Promotes immune evasion and resistance to Anti-PD-1 therapy in liver metastasis

WNT11 Promotes immune evasion and resistance to Anti-PD-1 therapy in liver metastasis

Abstract Liver metastasis (LM) poses a significant challenge in cancer treatment, with limited available therapeutic options and poor prognosis. Understanding the dynamics of tumor microenvironment (TME) and immune interactions is crucial for developing effective treatments. We find that WNT11 promo...

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Bibliographic Details
Main Authors: Weiliang Jiang, Bingjie Guan, Hongcheng Sun, Yushuai Mi, Sanjun Cai, Rong Wan, Xinxiang Li, Peng Lian, Dawei Li, Senlin Zhao
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56714-z
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