Determination of Iridotrabecular Contact Using the Anterior Segment Optical Coherence Tomography in Lights-on and Lights-off Conditions
Objective: To determine the presence of iridotrabecular contact (ITC) and compare the changes in anterior chamber angle (ACA) measurements in room lights-on and lights-off conditions using the anterior segment optical coherence tomography (AS-OCT) in eyes diagnosed as primary angle closure suspects...
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Philippine Academy of Ophthalmology
2019-06-01
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| Series: | Philippine Journal of Ophthalmology |
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| Online Access: | https://paojournal.com/index.php/pjo/article/view/112 |
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| author | James Paul S. Gomez, MD, DPBO Edgar U. Leuenberger, MD, DPBO |
| author_facet | James Paul S. Gomez, MD, DPBO Edgar U. Leuenberger, MD, DPBO |
| author_sort | James Paul S. Gomez, MD, DPBO |
| collection | DOAJ |
| description | Objective: To determine the presence of iridotrabecular contact (ITC) and compare the changes in anterior chamber angle (ACA) measurements in room lights-on and lights-off conditions using the anterior segment optical coherence tomography (AS-OCT) in eyes diagnosed as primary angle closure suspects (PACS) by gonioscopy.
Methods: This is a retrospective review of 144 eyes of 79 patients (70 females, 9 males) with PACS. All eyes were imaged using the Visante® time-domain AS-OCT (Carl Zeiss Meditec, Dublin, CA). Each eye was imaged twice; the first scan was done with the room lights on followed by a second scan done after turning the room lights off for 2 minutes. The principal outcome measure was the presence of ITC in either lighting condition. Other angle metrics that were assessed included anterior chamber depth (ACD), angle opening distance (AOD), trabecular-iris space area (TISA), and scleral spur angle (SSA). Presence of ITC and differences in the angle metrics between the 2 lighting conditions were then analyzed using the t-tests and logistic regression.
Results: ITC was present in 36.8% (53) of the study eyes. Twenty percent (20%) of the study eyes (29) did not initially exhibit ITC in the lights-on phase but developed ITC when imaged with the lights off. Persistent ITC was seen in 16.6% (24 eyes) in both lighting conditions. ITC occurred in 52.2% of the eyes with ACD less than 2.18 mm. Logistic regression showed that there is a 91% decrease in the odds of having ITC in lights-off condition for every millimeter of ACD increase. Age was not associated with the occurrence of ITC in the lights-off condition. All other analyzed parameters decreased significantly in the lights-off condition (p<0.05) except for the ACD, nasal TISA-500, and temporal SSA.
Conclusions: The presence of ITC is a well-established characteristic of eyes with angle closure. In eyes with PACS, detection of ITC may be enhanced with AS-OCT imaging in lights-off condition. |
| format | Article |
| id | doaj-art-d769ab0c6d8a4e85b171555d39dbef43 |
| institution | OA Journals |
| issn | 0031-7659 |
| language | English |
| publishDate | 2019-06-01 |
| publisher | Philippine Academy of Ophthalmology |
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| series | Philippine Journal of Ophthalmology |
| spelling | doaj-art-d769ab0c6d8a4e85b171555d39dbef432025-08-20T01:49:15ZengPhilippine Academy of OphthalmologyPhilippine Journal of Ophthalmology0031-76592019-06-014411924112Determination of Iridotrabecular Contact Using the Anterior Segment Optical Coherence Tomography in Lights-on and Lights-off ConditionsJames Paul S. Gomez, MD, DPBO0Edgar U. Leuenberger, MD, DPBO1Asian Eye Institute Phinma Plaza Building, Hidalgo Drive Rockwell, Makati, Metro ManilaAsian Eye Institute Phinma Plaza Building, Hidalgo Drive Rockwell, Makati, Metro ManilaObjective: To determine the presence of iridotrabecular contact (ITC) and compare the changes in anterior chamber angle (ACA) measurements in room lights-on and lights-off conditions using the anterior segment optical coherence tomography (AS-OCT) in eyes diagnosed as primary angle closure suspects (PACS) by gonioscopy. Methods: This is a retrospective review of 144 eyes of 79 patients (70 females, 9 males) with PACS. All eyes were imaged using the Visante® time-domain AS-OCT (Carl Zeiss Meditec, Dublin, CA). Each eye was imaged twice; the first scan was done with the room lights on followed by a second scan done after turning the room lights off for 2 minutes. The principal outcome measure was the presence of ITC in either lighting condition. Other angle metrics that were assessed included anterior chamber depth (ACD), angle opening distance (AOD), trabecular-iris space area (TISA), and scleral spur angle (SSA). Presence of ITC and differences in the angle metrics between the 2 lighting conditions were then analyzed using the t-tests and logistic regression. Results: ITC was present in 36.8% (53) of the study eyes. Twenty percent (20%) of the study eyes (29) did not initially exhibit ITC in the lights-on phase but developed ITC when imaged with the lights off. Persistent ITC was seen in 16.6% (24 eyes) in both lighting conditions. ITC occurred in 52.2% of the eyes with ACD less than 2.18 mm. Logistic regression showed that there is a 91% decrease in the odds of having ITC in lights-off condition for every millimeter of ACD increase. Age was not associated with the occurrence of ITC in the lights-off condition. All other analyzed parameters decreased significantly in the lights-off condition (p<0.05) except for the ACD, nasal TISA-500, and temporal SSA. Conclusions: The presence of ITC is a well-established characteristic of eyes with angle closure. In eyes with PACS, detection of ITC may be enhanced with AS-OCT imaging in lights-off condition.https://paojournal.com/index.php/pjo/article/view/112iridotrabecular contactas-octangle metrics |
| spellingShingle | James Paul S. Gomez, MD, DPBO Edgar U. Leuenberger, MD, DPBO Determination of Iridotrabecular Contact Using the Anterior Segment Optical Coherence Tomography in Lights-on and Lights-off Conditions Philippine Journal of Ophthalmology iridotrabecular contact as-oct angle metrics |
| title | Determination of Iridotrabecular Contact Using the Anterior Segment Optical Coherence Tomography in Lights-on and Lights-off Conditions |
| title_full | Determination of Iridotrabecular Contact Using the Anterior Segment Optical Coherence Tomography in Lights-on and Lights-off Conditions |
| title_fullStr | Determination of Iridotrabecular Contact Using the Anterior Segment Optical Coherence Tomography in Lights-on and Lights-off Conditions |
| title_full_unstemmed | Determination of Iridotrabecular Contact Using the Anterior Segment Optical Coherence Tomography in Lights-on and Lights-off Conditions |
| title_short | Determination of Iridotrabecular Contact Using the Anterior Segment Optical Coherence Tomography in Lights-on and Lights-off Conditions |
| title_sort | determination of iridotrabecular contact using the anterior segment optical coherence tomography in lights on and lights off conditions |
| topic | iridotrabecular contact as-oct angle metrics |
| url | https://paojournal.com/index.php/pjo/article/view/112 |
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