Comparative Analysis of Acute Effects of Different Aerobic Exercises on Clinical Symptoms and Cytokine Levels in Patients with Allergic Rhinitis: A Randomized Crossover Study
Introduction: Aerobic exercise has been shown to improve allergic symptoms. The purpose of this study was to investigate the impact of various moderate-intensity aerobic exercises on clinical symptoms and cytokines. Methods: Fifteen allergic rhinitis patients aged between 18 and 35 years were random...
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Ubiquity Press
2025-07-01
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| Series: | Physical Activity and Health |
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| author | Wannaporn Tongtako Jettanong Klaewsongkram Timothy D. Mickleborough Daroonwan Suksom |
| author_facet | Wannaporn Tongtako Jettanong Klaewsongkram Timothy D. Mickleborough Daroonwan Suksom |
| author_sort | Wannaporn Tongtako |
| collection | DOAJ |
| description | Introduction: Aerobic exercise has been shown to improve allergic symptoms. The purpose of this study was to investigate the impact of various moderate-intensity aerobic exercises on clinical symptoms and cytokines. Methods: Fifteen allergic rhinitis patients aged between 18 and 35 years were randomly assigned to complete three experimental sessions of aerobic exercise: running, cycling, and swimming. Physiological, symptoms, nasal blood flow (NBF), peak nasal inspiratory flow (PNIF), and cytokines variables were examined pre- and post-exercise. Statistical analyses included the Two-way ANOVA and Linear Mixed Model (LMM), with significance set at p < 0.05. Results: The results showed that all exercise protocols significantly reduced total rhinitis symptoms and itching scores compared to pre-test levels. Running notably decreased nasal congestion, sneezing, and rhinorrhea scores, while cycling and swimming each decreased specific symptoms. Both running and cycling exercises significantly altered NBF and PNIF. Furthermore, running exercise significantly reduced levels of various cytokines, whereas cycling and swimming exercises had more limited effects on cytokine levels. Conclusion: Moderate-intensity aerobic exercises, including running, cycling, and swimming, effectively alleviate rhinitis symptoms. Running stands out as particularly effective in reducing all symptoms and lowering pro-inflammatory cytokine levels. Thus, moderate running appears to be a suitable aerobic exercise option for individuals with allergic rhinitis. |
| format | Article |
| id | doaj-art-d7698fdf5a3c468f816ea2b3501d1d23 |
| institution | Kabale University |
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| language | English |
| publishDate | 2025-07-01 |
| publisher | Ubiquity Press |
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| series | Physical Activity and Health |
| spelling | doaj-art-d7698fdf5a3c468f816ea2b3501d1d232025-08-21T12:45:45ZengUbiquity PressPhysical Activity and Health2515-22702025-07-0191132–145132–14510.5334/paah.429429Comparative Analysis of Acute Effects of Different Aerobic Exercises on Clinical Symptoms and Cytokine Levels in Patients with Allergic Rhinitis: A Randomized Crossover StudyWannaporn Tongtako0https://orcid.org/0000-0003-4385-2468Jettanong Klaewsongkram1https://orcid.org/0000-0001-6063-2403Timothy D. Mickleborough2https://orcid.org/0000-0002-5118-268XDaroonwan Suksom3https://orcid.org/0000-0001-9668-3317Area of Exercise Physiology, Faculty of Sports Science, Chulalongkorn University, Bangkok; Center of Excellence in Exercise Physiology for Special Populations, Chulalongkorn University, BangkokDivision of Allergy and Clinical Immunology, Department of Medicine, Faculty of Medicine, Allergy and Clinical Immunology Research Group, Chulalongkorn University, BangkokDepartment of Kinesiology, School of Public Health, Indiana University, Bloomington, IndianaArea of Exercise Physiology, Faculty of Sports Science, Chulalongkorn University, Bangkok; Center of Excellence in Exercise Physiology for Special Populations, Chulalongkorn University, BangkokIntroduction: Aerobic exercise has been shown to improve allergic symptoms. The purpose of this study was to investigate the impact of various moderate-intensity aerobic exercises on clinical symptoms and cytokines. Methods: Fifteen allergic rhinitis patients aged between 18 and 35 years were randomly assigned to complete three experimental sessions of aerobic exercise: running, cycling, and swimming. Physiological, symptoms, nasal blood flow (NBF), peak nasal inspiratory flow (PNIF), and cytokines variables were examined pre- and post-exercise. Statistical analyses included the Two-way ANOVA and Linear Mixed Model (LMM), with significance set at p < 0.05. Results: The results showed that all exercise protocols significantly reduced total rhinitis symptoms and itching scores compared to pre-test levels. Running notably decreased nasal congestion, sneezing, and rhinorrhea scores, while cycling and swimming each decreased specific symptoms. Both running and cycling exercises significantly altered NBF and PNIF. Furthermore, running exercise significantly reduced levels of various cytokines, whereas cycling and swimming exercises had more limited effects on cytokine levels. Conclusion: Moderate-intensity aerobic exercises, including running, cycling, and swimming, effectively alleviate rhinitis symptoms. Running stands out as particularly effective in reducing all symptoms and lowering pro-inflammatory cytokine levels. Thus, moderate running appears to be a suitable aerobic exercise option for individuals with allergic rhinitis.https://account.paahjournal.com/index.php/up-j-pah/article/view/429runningcyclingswimmingcytokinesnasal blood flow |
| spellingShingle | Wannaporn Tongtako Jettanong Klaewsongkram Timothy D. Mickleborough Daroonwan Suksom Comparative Analysis of Acute Effects of Different Aerobic Exercises on Clinical Symptoms and Cytokine Levels in Patients with Allergic Rhinitis: A Randomized Crossover Study Physical Activity and Health running cycling swimming cytokines nasal blood flow |
| title | Comparative Analysis of Acute Effects of Different Aerobic Exercises on Clinical Symptoms and Cytokine Levels in Patients with Allergic Rhinitis: A Randomized Crossover Study |
| title_full | Comparative Analysis of Acute Effects of Different Aerobic Exercises on Clinical Symptoms and Cytokine Levels in Patients with Allergic Rhinitis: A Randomized Crossover Study |
| title_fullStr | Comparative Analysis of Acute Effects of Different Aerobic Exercises on Clinical Symptoms and Cytokine Levels in Patients with Allergic Rhinitis: A Randomized Crossover Study |
| title_full_unstemmed | Comparative Analysis of Acute Effects of Different Aerobic Exercises on Clinical Symptoms and Cytokine Levels in Patients with Allergic Rhinitis: A Randomized Crossover Study |
| title_short | Comparative Analysis of Acute Effects of Different Aerobic Exercises on Clinical Symptoms and Cytokine Levels in Patients with Allergic Rhinitis: A Randomized Crossover Study |
| title_sort | comparative analysis of acute effects of different aerobic exercises on clinical symptoms and cytokine levels in patients with allergic rhinitis a randomized crossover study |
| topic | running cycling swimming cytokines nasal blood flow |
| url | https://account.paahjournal.com/index.php/up-j-pah/article/view/429 |
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