Mucormycosis in a Renal Transplant Recipient: Case Report and Comprehensive Review of Literature
Mucormycosis is a rare but devastating infection. We present a case of fatal disseminated mucormycosis infection in a renal transplant patient. Uncontrolled diabetes mellitus and immunosuppression are the major predisposing factors to infection with Mucorales. Mucorales are angioinvasive and can inf...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2014-01-01
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| Series: | International Journal of Nephrology |
| Online Access: | http://dx.doi.org/10.1155/2014/950643 |
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| _version_ | 1850172075852955648 |
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| author | Tamim Hamdi Vanji Karthikeyan George J. Alangaden |
| author_facet | Tamim Hamdi Vanji Karthikeyan George J. Alangaden |
| author_sort | Tamim Hamdi |
| collection | DOAJ |
| description | Mucormycosis is a rare but devastating infection. We present a case of fatal disseminated mucormycosis infection in a renal transplant patient. Uncontrolled diabetes mellitus and immunosuppression are the major predisposing factors to infection with Mucorales. Mucorales are angioinvasive and can infect any organ system. Lungs are the predominant site of infection in solid organ transplant recipients. Prompt diagnosis is challenging and influences outcome. Treatment involves a combination of surgical and medical therapies. Amphotericin B remains the cornerstone in the medical management of mucormycosis, although other agents have been used. Newer agents are promising. |
| format | Article |
| id | doaj-art-d76403bd325b4deeabd336cb40e84630 |
| institution | OA Journals |
| issn | 2090-214X 2090-2158 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Nephrology |
| spelling | doaj-art-d76403bd325b4deeabd336cb40e846302025-08-20T02:20:09ZengWileyInternational Journal of Nephrology2090-214X2090-21582014-01-01201410.1155/2014/950643950643Mucormycosis in a Renal Transplant Recipient: Case Report and Comprehensive Review of LiteratureTamim Hamdi0Vanji Karthikeyan1George J. Alangaden2Division of Nephrology and Hypertension, Department of Internal Medicine, Henry Ford Hospital, 2799 West Grand Boulevard, CFP-514, Detroit, MI 48202, USADivision of Nephrology and Hypertension, Department of Internal Medicine, Henry Ford Hospital, 2799 West Grand Boulevard, CFP-514, Detroit, MI 48202, USADivision of Infectious Diseases, Department of Internal Medicine, Henry Ford Hospital, Detroit, MI 48202, USAMucormycosis is a rare but devastating infection. We present a case of fatal disseminated mucormycosis infection in a renal transplant patient. Uncontrolled diabetes mellitus and immunosuppression are the major predisposing factors to infection with Mucorales. Mucorales are angioinvasive and can infect any organ system. Lungs are the predominant site of infection in solid organ transplant recipients. Prompt diagnosis is challenging and influences outcome. Treatment involves a combination of surgical and medical therapies. Amphotericin B remains the cornerstone in the medical management of mucormycosis, although other agents have been used. Newer agents are promising.http://dx.doi.org/10.1155/2014/950643 |
| spellingShingle | Tamim Hamdi Vanji Karthikeyan George J. Alangaden Mucormycosis in a Renal Transplant Recipient: Case Report and Comprehensive Review of Literature International Journal of Nephrology |
| title | Mucormycosis in a Renal Transplant Recipient: Case Report and Comprehensive Review of Literature |
| title_full | Mucormycosis in a Renal Transplant Recipient: Case Report and Comprehensive Review of Literature |
| title_fullStr | Mucormycosis in a Renal Transplant Recipient: Case Report and Comprehensive Review of Literature |
| title_full_unstemmed | Mucormycosis in a Renal Transplant Recipient: Case Report and Comprehensive Review of Literature |
| title_short | Mucormycosis in a Renal Transplant Recipient: Case Report and Comprehensive Review of Literature |
| title_sort | mucormycosis in a renal transplant recipient case report and comprehensive review of literature |
| url | http://dx.doi.org/10.1155/2014/950643 |
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