Effect of valproic acid upon skeletal muscle subjected to prolonged tourniquet application
Background Valproic acid (VPA), a histone deacetylase inhibitor, has shown improved outcomes when used as a pharmaceutical intervention in animal studies of hemorrhage, septic shock, and combined injuries. This study was designed to investigate the ability of VPA to mitigate ischemia–reperfusion inj...
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| Main Authors: | Robert Moritz, Lee Mangum, Chet Voelker, Gerardo Garcia, Joseph Wenke |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
2023-12-01
|
| Series: | Trauma Surgery & Acute Care Open |
| Online Access: | https://tsaco.bmj.com/content/8/1/e001074.full |
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