Edaravone Dexborneol provides neuroprotective effect by inhibiting neurotoxic activation of astrocytes through inhibiting NF-κB signaling in cortical ischemia
Edaravone Dexborneol (EDB), comprised of edaravone and (+)- bornel, has been demonstrated to have synergistic effects of antioxidant and anti-inflammatory, which makes it to be applied for stroke as a protectant. However, the underlying mechanism of neuroprotection of EDB has not been fully elucidat...
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| Main Authors: | Zhe Chen, Tao Li, Hai-Bin Tang, Zi-Wei Lu, Zi-Yi Chen, Zhi-Hong Zhao, Xue-Ling Yang, Li-Li Zhao, Mei-Juan Dang, Ye Li, Wen-Xian Li, Xiao-Juan Wang, Peng-Peng Jiang, Shu-Qin Zhan, Gui-Lian Zhang, Hong Fan |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-11-01
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| Series: | Brain Research Bulletin |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0361923024002314 |
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