Identification of a novel SNP mutation causing drop-out alleles in a paternity test using combined nest and touch-down PCR with Sanger sequencing

Identification of a novel SNP mutation causing drop-out alleles in a paternity test using combined nest and touch-down PCR with Sanger sequencing

Background Short tandem repeat (STR) markers are widely used in forensic DNA analysis due to their ability to provide automated and standardised typing. However, incorrect STR typing can have a significant impact on forensic outcomes.Aim In this study, we detected drop-out alleles at the SE33 locus...

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Bibliographic Details
Main Authors: Hongbo Wang, Botong Shi, Liang Guo, Yingnan Zou, Bo Liu, Jun Yao, Baojie Wang, Zhengdong Wang, Xin Li, Gang Mu, Fu Ren
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Annals of Human Biology
Subjects:
Forensic genetics
SE33 locus
SNP mutation
Drop-out alleles
Online Access:https://www.tandfonline.com/doi/10.1080/03014460.2024.2418591
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