A case report unveiling spindle cell lipoma

Spindle cell lipoma (SCL) represents an infrequent subtype of lipoma distinguished by its distinctive histopathological characteristics and tendency to localize in the subcutaneous tissues of the upper back, neck, and shoulder regions. In this report, we describe an unusual instance of SCL manifesti...

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Main Authors: Sakshi Dudhe, MBBS, Devyansh Nimodia, MBBS, Gaurav V. Mishra, MD, Pratapsingh Hanuman Parihar, MD, Paritosh Bhangale, MBBS, Anjali Kumari, MBBS, Rishitha Kotla, MBBS
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Radiology Case Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S1930043325002195
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author Sakshi Dudhe, MBBS
Devyansh Nimodia, MBBS
Gaurav V. Mishra, MD
Pratapsingh Hanuman Parihar, MD
Paritosh Bhangale, MBBS
Anjali Kumari, MBBS
Rishitha Kotla, MBBS
author_facet Sakshi Dudhe, MBBS
Devyansh Nimodia, MBBS
Gaurav V. Mishra, MD
Pratapsingh Hanuman Parihar, MD
Paritosh Bhangale, MBBS
Anjali Kumari, MBBS
Rishitha Kotla, MBBS
author_sort Sakshi Dudhe, MBBS
collection DOAJ
description Spindle cell lipoma (SCL) represents an infrequent subtype of lipoma distinguished by its distinctive histopathological characteristics and tendency to localize in the subcutaneous tissues of the upper back, neck, and shoulder regions. In this report, we describe an unusual instance of SCL manifesting in the cervical area of a 62-year-old female individual. The patient exhibited a progressively enlarging painless mass situated in the left supraclavicular region for 8 years. Radiographic assessments disclosed a clearly demarcated, enclosed mass indicative of a lipomatous lesion. Microscopic analysis of the surgically removed specimen verified the presence of SCL, featuring mature adipocytes interspersed with spindle cells and collagen fibers. Subsequent immunohistochemical testing corroborated the diagnosis through the detection of CD34 positivity and S-100 protein negativity. Subsequent to surgical excision, the patient experienced an uneventful recovery period, devoid of any signs of recurrence throughout the monitoring phase. Despite its rarity, SCL should be contemplated in the differential diagnosis of neck masses, particularly when radiological findings point towards adipose tissue-related neoplasms. Timely identification and suitable intervention play a pivotal role in ensuring positive prognoses for individuals afflicted with SCL in the neck region
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spelling doaj-art-d744d428d37541d6bbf633273c19033f2025-08-20T03:03:38ZengElsevierRadiology Case Reports1930-04332025-06-012063010301510.1016/j.radcr.2025.03.009A case report unveiling spindle cell lipomaSakshi Dudhe, MBBS0Devyansh Nimodia, MBBS1Gaurav V. Mishra, MD2Pratapsingh Hanuman Parihar, MD3Paritosh Bhangale, MBBS4Anjali Kumari, MBBS5Rishitha Kotla, MBBS6Department of Radiodiagnosis, Datta Meghe Institute of Medical Sciences, Wardha, Maharashtra, India, 442001; Corresponding author.Department of Radiodiagnosis, Datta Meghe Institute of Medical Sciences, Wardha, Maharashtra, India, 442001Department of Radiodiagnosis, Datta Meghe Institute of Medical Sciences, Wardha, Maharashtra, India, 442001Department of Radiodiagnosis, Datta Meghe Institute of Medical Sciences, Wardha, Maharashtra, India, 442001Department of Radiodiagnosis, Datta Meghe Institute of Medical Sciences, Wardha, Maharashtra, India, 442001Department of Radiodiagnosis, Datta Meghe Institute of Medical Sciences, Wardha, Maharashtra, India, 442001Department of Psychiatry, Datta Meghe Institute of Medical Sciences, Wardha, Maharashtra, India, 442001Spindle cell lipoma (SCL) represents an infrequent subtype of lipoma distinguished by its distinctive histopathological characteristics and tendency to localize in the subcutaneous tissues of the upper back, neck, and shoulder regions. In this report, we describe an unusual instance of SCL manifesting in the cervical area of a 62-year-old female individual. The patient exhibited a progressively enlarging painless mass situated in the left supraclavicular region for 8 years. Radiographic assessments disclosed a clearly demarcated, enclosed mass indicative of a lipomatous lesion. Microscopic analysis of the surgically removed specimen verified the presence of SCL, featuring mature adipocytes interspersed with spindle cells and collagen fibers. Subsequent immunohistochemical testing corroborated the diagnosis through the detection of CD34 positivity and S-100 protein negativity. Subsequent to surgical excision, the patient experienced an uneventful recovery period, devoid of any signs of recurrence throughout the monitoring phase. Despite its rarity, SCL should be contemplated in the differential diagnosis of neck masses, particularly when radiological findings point towards adipose tissue-related neoplasms. Timely identification and suitable intervention play a pivotal role in ensuring positive prognoses for individuals afflicted with SCL in the neck regionhttp://www.sciencedirect.com/science/article/pii/S1930043325002195SpindleLipomaSurgeryBenignCTRadiology
spellingShingle Sakshi Dudhe, MBBS
Devyansh Nimodia, MBBS
Gaurav V. Mishra, MD
Pratapsingh Hanuman Parihar, MD
Paritosh Bhangale, MBBS
Anjali Kumari, MBBS
Rishitha Kotla, MBBS
A case report unveiling spindle cell lipoma
Radiology Case Reports
Spindle
Lipoma
Surgery
Benign
CT
Radiology
title A case report unveiling spindle cell lipoma
title_full A case report unveiling spindle cell lipoma
title_fullStr A case report unveiling spindle cell lipoma
title_full_unstemmed A case report unveiling spindle cell lipoma
title_short A case report unveiling spindle cell lipoma
title_sort case report unveiling spindle cell lipoma
topic Spindle
Lipoma
Surgery
Benign
CT
Radiology
url http://www.sciencedirect.com/science/article/pii/S1930043325002195
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