N-glycosylation of ACTRIIB enhances protein stability leading to rapid cell proliferation and strong resistance to docetaxel in nasopharyngeal carcinoma

N-glycosylation of ACTRIIB enhances protein stability leading to rapid cell proliferation and strong resistance to docetaxel in nasopharyngeal carcinoma

Nasopharyngeal carcinoma (NPC) is a malignant tumor predominantly influenced by Epstein-Barr virus infection and genetic factors. The transforming growth factor-beta (TGF-β) superfamily is implicated in various cellular processes, including tumorigenesis. This study aimed to detect the role of one T...

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Bibliographic Details
Main Authors: Qin Qin, Junfeng Li, Yinjian Shao, Lan Liu, Zhibin Luo
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2025-02-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
N-glycosylation
ACTRIIB
Nasopharyngeal carcinoma
Docetaxel
Membrane localization
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2025000100612&lng=en&tlng=en
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