LONG-TERM RESULTS OF THE VALVE-SAVING SURGERY IN MARFAN SYNDROME PATIENTS
The main causes of mortality and morbidity in Marfan syndrome patients are cardiovascular complications. The Bentall DeBono operation for long time has been a gold standard treatment for this pathology.Aim. To present the obvious benefits of valve-saving surgery stimulating for saving of aorta valve...
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«FIRMA «SILICEA» LLC
2016-11-01
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| Series: | Российский кардиологический журнал |
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| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/964 |
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| author | D. S. Khvan A. M. Chernyavskiy D. A. Sirota S. A. Alsov M. M. Lyashenko |
| author_facet | D. S. Khvan A. M. Chernyavskiy D. A. Sirota S. A. Alsov M. M. Lyashenko |
| author_sort | D. S. Khvan |
| collection | DOAJ |
| description | The main causes of mortality and morbidity in Marfan syndrome patients are cardiovascular complications. The Bentall DeBono operation for long time has been a gold standard treatment for this pathology.Aim. To present the obvious benefits of valve-saving surgery stimulating for saving of aorta valve (AoV) in dysplasia of connective tissue.Material and methods. A single-center retrospective analysis was done, of the results of valve-saving operations on the aorta root. All Marfan syndrome patients were included, who had undergone valve-saving operation on AoV in 2007-2015 y. As the valve-saving operation the David method was used, operation of reimplanting of aorta root into prosthesis and supracoronary prosthesing of ascending aorta.Results. Nine-year freedom from aortic regurgitation more 2 grade in long-term follow-up was 64%. As the a causes for development of aortic valve insufficiency were progressing degenerations of AoV. There were no cases of bleedings and endocarditis. Expected cumulative survival was 63%.Conclusion. Valve-saving operations are applicable in patients with the syndrome of connective tissue dysplasia. However, the worth of valve-saving operations in Marfan syndrome is questionable. Taken the known data, the studies demanded, with more number of patients and longer follow-up. |
| format | Article |
| id | doaj-art-d72b90dcbf8c4319a1bd9290df85fd40 |
| institution | Kabale University |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| publishDate | 2016-11-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj-art-d72b90dcbf8c4319a1bd9290df85fd402025-08-20T03:43:37Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202016-11-01011121510.15829/1560-4071-2016-11-12-15817LONG-TERM RESULTS OF THE VALVE-SAVING SURGERY IN MARFAN SYNDROME PATIENTSD. S. Khvan0A. M. Chernyavskiy1D. A. Sirota2S. A. Alsov3M. M. Lyashenko4Center for Surgery of Aorta, Coronary and Peripheral Arteries, E. N. Meshalkin Novosibirsk Scientific-Research Institute of Circulation Pathology, Novosibirsk, RussiaCenter for Surgery of Aorta, Coronary and Peripheral Arteries, E. N. Meshalkin Novosibirsk Scientific-Research Institute of Circulation Pathology, Novosibirsk, RussiaCenter for Surgery of Aorta, Coronary and Peripheral Arteries, E. N. Meshalkin Novosibirsk Scientific-Research Institute of Circulation Pathology, Novosibirsk, RussiaCenter for Surgery of Aorta, Coronary and Peripheral Arteries, E. N. Meshalkin Novosibirsk Scientific-Research Institute of Circulation Pathology, Novosibirsk, RussiaCenter for Surgery of Aorta, Coronary and Peripheral Arteries, E. N. Meshalkin Novosibirsk Scientific-Research Institute of Circulation Pathology, Novosibirsk, RussiaThe main causes of mortality and morbidity in Marfan syndrome patients are cardiovascular complications. The Bentall DeBono operation for long time has been a gold standard treatment for this pathology.Aim. To present the obvious benefits of valve-saving surgery stimulating for saving of aorta valve (AoV) in dysplasia of connective tissue.Material and methods. A single-center retrospective analysis was done, of the results of valve-saving operations on the aorta root. All Marfan syndrome patients were included, who had undergone valve-saving operation on AoV in 2007-2015 y. As the valve-saving operation the David method was used, operation of reimplanting of aorta root into prosthesis and supracoronary prosthesing of ascending aorta.Results. Nine-year freedom from aortic regurgitation more 2 grade in long-term follow-up was 64%. As the a causes for development of aortic valve insufficiency were progressing degenerations of AoV. There were no cases of bleedings and endocarditis. Expected cumulative survival was 63%.Conclusion. Valve-saving operations are applicable in patients with the syndrome of connective tissue dysplasia. However, the worth of valve-saving operations in Marfan syndrome is questionable. Taken the known data, the studies demanded, with more number of patients and longer follow-up.https://russjcardiol.elpub.ru/jour/article/view/964aortaaortic regurgitationvalve-saving surgerymarfan syndrome |
| spellingShingle | D. S. Khvan A. M. Chernyavskiy D. A. Sirota S. A. Alsov M. M. Lyashenko LONG-TERM RESULTS OF THE VALVE-SAVING SURGERY IN MARFAN SYNDROME PATIENTS Российский кардиологический журнал aorta aortic regurgitation valve-saving surgery marfan syndrome |
| title | LONG-TERM RESULTS OF THE VALVE-SAVING SURGERY IN MARFAN SYNDROME PATIENTS |
| title_full | LONG-TERM RESULTS OF THE VALVE-SAVING SURGERY IN MARFAN SYNDROME PATIENTS |
| title_fullStr | LONG-TERM RESULTS OF THE VALVE-SAVING SURGERY IN MARFAN SYNDROME PATIENTS |
| title_full_unstemmed | LONG-TERM RESULTS OF THE VALVE-SAVING SURGERY IN MARFAN SYNDROME PATIENTS |
| title_short | LONG-TERM RESULTS OF THE VALVE-SAVING SURGERY IN MARFAN SYNDROME PATIENTS |
| title_sort | long term results of the valve saving surgery in marfan syndrome patients |
| topic | aorta aortic regurgitation valve-saving surgery marfan syndrome |
| url | https://russjcardiol.elpub.ru/jour/article/view/964 |
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