Investigation of the modification of gold electrodes by electrochemical molecularly imprinted polymers as a selective layer for the trace level electroanalysis of PAH

Electrochemical molecularly imprinted polymers (e-MIPs) were grafted for the first time as a thin layer to the surface of a gold electrode to perform trace level electroanalysis of benzo(a)pyrene (BaP). This was achieved by controlled/living radical photopolymerization of a redox tracer monomer (fer...

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Main Authors: Farah Ibrahim, Alexandre Sala, Armand Fahs, Aoife Morrin, Clément Nanteuil, Guillaume Laffite, Ian A. Nicholls, Fiona Regan, Hugues Brisset, Catherine Branger
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Electrochemistry Communications
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Online Access:http://www.sciencedirect.com/science/article/pii/S1388248124001802
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author Farah Ibrahim
Alexandre Sala
Armand Fahs
Aoife Morrin
Clément Nanteuil
Guillaume Laffite
Ian A. Nicholls
Fiona Regan
Hugues Brisset
Catherine Branger
author_facet Farah Ibrahim
Alexandre Sala
Armand Fahs
Aoife Morrin
Clément Nanteuil
Guillaume Laffite
Ian A. Nicholls
Fiona Regan
Hugues Brisset
Catherine Branger
author_sort Farah Ibrahim
collection DOAJ
description Electrochemical molecularly imprinted polymers (e-MIPs) were grafted for the first time as a thin layer to the surface of a gold electrode to perform trace level electroanalysis of benzo(a)pyrene (BaP). This was achieved by controlled/living radical photopolymerization of a redox tracer monomer (ferrocenylmethyl methacrylate, FcMMA) with ethylene glycol dimethacrylate in the presence of benzo(a)pyrene as the template molecule. For that purpose, a novel photoiniferter-derived SAM was first deposited on the gold surface. The SAM formation was monitored by cyclic voltammetry and electrochemical impedance spectroscopy. Then, the “grafting from” of the e-MIP was achieved upon photoirradiation during a controlled time. Differential pulse voltammetry was used to quantify BaP in aqueous solution by following the modification of the signal of FcMMA. A limit of detection of 0.19 nM in water and a linear range of 0.66 nM to 4.30 nM, were determined, thus validating the enhancement of sensitivity induced by the close contact between the e-MIP and the electrode, and the improved transfer electron.
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spelling doaj-art-d729fa546d6f4d308e439ea42357d3e72025-08-20T01:54:15ZengElsevierElectrochemistry Communications1388-24812024-12-0116910783710.1016/j.elecom.2024.107837Investigation of the modification of gold electrodes by electrochemical molecularly imprinted polymers as a selective layer for the trace level electroanalysis of PAHFarah Ibrahim0Alexandre Sala1Armand Fahs2Aoife Morrin3Clément Nanteuil4Guillaume Laffite5Ian A. Nicholls6Fiona Regan7Hugues Brisset8Catherine Branger9Université de Toulon, Laboratoire Matériaux Polymères Interfaces Environnement Marin (MAPIEM), Toulon, FranceUniversité de Toulon, Laboratoire Matériaux Polymères Interfaces Environnement Marin (MAPIEM), Toulon, FranceUniversité de Toulon, Laboratoire Matériaux Polymères Interfaces Environnement Marin (MAPIEM), Toulon, FranceSchool of Chemical Sciences, DCU Water Institute, Dublin City University, Glasnevin, Dublin 9, IrelandKlearia, 61 Avenue Simone Veil, CEEI Nice Côte d’Azur - Immeuble Premium, 06200 Nice, FranceKlearia, 61 Avenue Simone Veil, CEEI Nice Côte d’Azur - Immeuble Premium, 06200 Nice, FranceBioorganic & Biophysical Chemistry Laboratory, Department of Chemistry & Biomedical Sciences, Linnaeus University, SE-39182 Kalmar, SwedenSchool of Chemical Sciences, DCU Water Institute, Dublin City University, Glasnevin, Dublin 9, IrelandUniversité de Toulon, Laboratoire Matériaux Polymères Interfaces Environnement Marin (MAPIEM), Toulon, FranceUniversité de Toulon, Laboratoire Matériaux Polymères Interfaces Environnement Marin (MAPIEM), Toulon, France; Corresponding author.Electrochemical molecularly imprinted polymers (e-MIPs) were grafted for the first time as a thin layer to the surface of a gold electrode to perform trace level electroanalysis of benzo(a)pyrene (BaP). This was achieved by controlled/living radical photopolymerization of a redox tracer monomer (ferrocenylmethyl methacrylate, FcMMA) with ethylene glycol dimethacrylate in the presence of benzo(a)pyrene as the template molecule. For that purpose, a novel photoiniferter-derived SAM was first deposited on the gold surface. The SAM formation was monitored by cyclic voltammetry and electrochemical impedance spectroscopy. Then, the “grafting from” of the e-MIP was achieved upon photoirradiation during a controlled time. Differential pulse voltammetry was used to quantify BaP in aqueous solution by following the modification of the signal of FcMMA. A limit of detection of 0.19 nM in water and a linear range of 0.66 nM to 4.30 nM, were determined, thus validating the enhancement of sensitivity induced by the close contact between the e-MIP and the electrode, and the improved transfer electron.http://www.sciencedirect.com/science/article/pii/S1388248124001802Molecularly imprinted polymers (MIPs)Electrochemical sensorBenzo(a)pyreneRedox probe
spellingShingle Farah Ibrahim
Alexandre Sala
Armand Fahs
Aoife Morrin
Clément Nanteuil
Guillaume Laffite
Ian A. Nicholls
Fiona Regan
Hugues Brisset
Catherine Branger
Investigation of the modification of gold electrodes by electrochemical molecularly imprinted polymers as a selective layer for the trace level electroanalysis of PAH
Electrochemistry Communications
Molecularly imprinted polymers (MIPs)
Electrochemical sensor
Benzo(a)pyrene
Redox probe
title Investigation of the modification of gold electrodes by electrochemical molecularly imprinted polymers as a selective layer for the trace level electroanalysis of PAH
title_full Investigation of the modification of gold electrodes by electrochemical molecularly imprinted polymers as a selective layer for the trace level electroanalysis of PAH
title_fullStr Investigation of the modification of gold electrodes by electrochemical molecularly imprinted polymers as a selective layer for the trace level electroanalysis of PAH
title_full_unstemmed Investigation of the modification of gold electrodes by electrochemical molecularly imprinted polymers as a selective layer for the trace level electroanalysis of PAH
title_short Investigation of the modification of gold electrodes by electrochemical molecularly imprinted polymers as a selective layer for the trace level electroanalysis of PAH
title_sort investigation of the modification of gold electrodes by electrochemical molecularly imprinted polymers as a selective layer for the trace level electroanalysis of pah
topic Molecularly imprinted polymers (MIPs)
Electrochemical sensor
Benzo(a)pyrene
Redox probe
url http://www.sciencedirect.com/science/article/pii/S1388248124001802
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