A Systematic Review on the Occurrence of <i>Babesia</i> spp. and <i>Anaplasma</i> spp. in Ticks and Wild Boar from Europe—A 15-Year Retrospective Study

The wild boar (<i>Sus scrofa</i>) has experienced significant population growth as well as geographic expansion across Europe over the past 15 years, leading to increased concerns regarding its role in the transmission of zoonotic pathogens. Among these, <i>Babesia</i> spp. a...

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Main Authors: Ioan Cristian Dreghiciu, Diana Hoffman, Tiana Florea, Ion Oprescu, Simona Dumitru, Mirela Imre, Vlad Iorgoni, Anamaria Plesko, Sorin Morariu, Marius Stelian Ilie
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Pathogens
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Online Access:https://www.mdpi.com/2076-0817/14/7/612
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author Ioan Cristian Dreghiciu
Diana Hoffman
Tiana Florea
Ion Oprescu
Simona Dumitru
Mirela Imre
Vlad Iorgoni
Anamaria Plesko
Sorin Morariu
Marius Stelian Ilie
author_facet Ioan Cristian Dreghiciu
Diana Hoffman
Tiana Florea
Ion Oprescu
Simona Dumitru
Mirela Imre
Vlad Iorgoni
Anamaria Plesko
Sorin Morariu
Marius Stelian Ilie
author_sort Ioan Cristian Dreghiciu
collection DOAJ
description The wild boar (<i>Sus scrofa</i>) has experienced significant population growth as well as geographic expansion across Europe over the past 15 years, leading to increased concerns regarding its role in the transmission of zoonotic pathogens. Among these, <i>Babesia</i> spp. and <i>Anaplasma</i> spp. are of particular importance due to their impact on both wildlife and domestic animals. This study systematically reviews the prevalence and distribution of <i>Babesia</i> and <i>Anaplasma</i> spp. in wild boars and associated tick vectors across multiple European countries, synthesizing data from literature published between 2010 and 2024. A comprehensive search of Scopus, Google Scholar, and PubMed databases was conducted using predefined keywords related to babesiosis, anaplasmosis, wild boars, Europe, and tick-borne diseases. A total of 281 studies were initially retrieved, of which 19 met the inclusion criteria following relevance assessment. Data extraction focused on pathogen identification, diagnostic methods, sample type, host species, and prevalence rates. Molecular detection methods, primarily PCR and sequencing, were the most used diagnostic tools. Results indicate substantial regional variations in the prevalence of <i>Babesia</i> and <i>Anaplasma</i> spp. <i>A. phagocytophilum</i> was detected in wild boar populations across multiple countries, with the highest prevalence rates observed in Slovakia (28.2%) and Poland (20.34%). Conversely, lower prevalence rates were recorded in France (2%) and Portugal (3.1%). <i>Babesia</i> spp. showed higher prevalence rates in Italy (6.2%), while its detection in other regions such as Romania and Spain was minimal or absent. Notably, spleen and multi-organ samples (spleen/liver/kidney) exhibited higher positivity rates compared to blood samples, suggesting an organotropic localization of these pathogens. The findings underscore the role of wild boars as reservoirs for tick-borne pathogens and highlight their potential to contribute to the epidemiological cycle of these infections. The increasing distribution of wild boars, coupled with climate-driven shifts in tick populations, may further facilitate pathogen transmission. Future studies should focus on integrating molecular, serological, and ecological approaches to improve surveillance and risk assessment. Standardized methodologies across different regions will be essential in enhancing comparative epidemiological insights and informing targeted disease management strategies.
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spelling doaj-art-d70e6d1f5b714ef484780da3fa9aed002025-08-20T03:08:02ZengMDPI AGPathogens2076-08172025-06-0114761210.3390/pathogens14070612A Systematic Review on the Occurrence of <i>Babesia</i> spp. and <i>Anaplasma</i> spp. in Ticks and Wild Boar from Europe—A 15-Year Retrospective StudyIoan Cristian Dreghiciu0Diana Hoffman1Tiana Florea2Ion Oprescu3Simona Dumitru4Mirela Imre5Vlad Iorgoni6Anamaria Plesko7Sorin Morariu8Marius Stelian Ilie9Department of Parasitology and Parasitic Disease, Faculty of Veterinary Medicine, University of Life Sciences “King Mihai I” of Timisoara, 119, Calea Aradului, 300645 Timisoara, RomaniaDepartment of Parasitology and Parasitic Disease, Faculty of Veterinary Medicine, University of Life Sciences “King Mihai I” of Timisoara, 119, Calea Aradului, 300645 Timisoara, RomaniaDepartment of Parasitology and Parasitic Disease, Faculty of Veterinary Medicine, University of Life Sciences “King Mihai I” of Timisoara, 119, Calea Aradului, 300645 Timisoara, RomaniaDepartment of Parasitology and Parasitic Disease, Faculty of Veterinary Medicine, University of Life Sciences “King Mihai I” of Timisoara, 119, Calea Aradului, 300645 Timisoara, RomaniaVeterinary and Food Safety Department 4, Surorile Martir Caceu, 300585 Timisoara, RomaniaDepartment of Parasitology and Parasitic Disease, Faculty of Veterinary Medicine, University of Life Sciences “King Mihai I” of Timisoara, 119, Calea Aradului, 300645 Timisoara, RomaniaDepartment of Infectious Diseases and Preventive Medicine, Faculty of Veterinary Medicine, University of Life Sciences “King Mihai I” of Timisoara, 119, Calea Aradului, 300645 Timisoara, RomaniaDepartment of Parasitology and Parasitic Disease, Faculty of Veterinary Medicine, University of Life Sciences “King Mihai I” of Timisoara, 119, Calea Aradului, 300645 Timisoara, RomaniaDepartment of Parasitology and Parasitic Disease, Faculty of Veterinary Medicine, University of Life Sciences “King Mihai I” of Timisoara, 119, Calea Aradului, 300645 Timisoara, RomaniaDepartment of Parasitology and Parasitic Disease, Faculty of Veterinary Medicine, University of Life Sciences “King Mihai I” of Timisoara, 119, Calea Aradului, 300645 Timisoara, RomaniaThe wild boar (<i>Sus scrofa</i>) has experienced significant population growth as well as geographic expansion across Europe over the past 15 years, leading to increased concerns regarding its role in the transmission of zoonotic pathogens. Among these, <i>Babesia</i> spp. and <i>Anaplasma</i> spp. are of particular importance due to their impact on both wildlife and domestic animals. This study systematically reviews the prevalence and distribution of <i>Babesia</i> and <i>Anaplasma</i> spp. in wild boars and associated tick vectors across multiple European countries, synthesizing data from literature published between 2010 and 2024. A comprehensive search of Scopus, Google Scholar, and PubMed databases was conducted using predefined keywords related to babesiosis, anaplasmosis, wild boars, Europe, and tick-borne diseases. A total of 281 studies were initially retrieved, of which 19 met the inclusion criteria following relevance assessment. Data extraction focused on pathogen identification, diagnostic methods, sample type, host species, and prevalence rates. Molecular detection methods, primarily PCR and sequencing, were the most used diagnostic tools. Results indicate substantial regional variations in the prevalence of <i>Babesia</i> and <i>Anaplasma</i> spp. <i>A. phagocytophilum</i> was detected in wild boar populations across multiple countries, with the highest prevalence rates observed in Slovakia (28.2%) and Poland (20.34%). Conversely, lower prevalence rates were recorded in France (2%) and Portugal (3.1%). <i>Babesia</i> spp. showed higher prevalence rates in Italy (6.2%), while its detection in other regions such as Romania and Spain was minimal or absent. Notably, spleen and multi-organ samples (spleen/liver/kidney) exhibited higher positivity rates compared to blood samples, suggesting an organotropic localization of these pathogens. The findings underscore the role of wild boars as reservoirs for tick-borne pathogens and highlight their potential to contribute to the epidemiological cycle of these infections. The increasing distribution of wild boars, coupled with climate-driven shifts in tick populations, may further facilitate pathogen transmission. Future studies should focus on integrating molecular, serological, and ecological approaches to improve surveillance and risk assessment. Standardized methodologies across different regions will be essential in enhancing comparative epidemiological insights and informing targeted disease management strategies.https://www.mdpi.com/2076-0817/14/7/612<i>Babesia</i> spp.<i>Anaplasma</i> spp.wild boartick-borne pathogenszoonotic diseasesEurope
spellingShingle Ioan Cristian Dreghiciu
Diana Hoffman
Tiana Florea
Ion Oprescu
Simona Dumitru
Mirela Imre
Vlad Iorgoni
Anamaria Plesko
Sorin Morariu
Marius Stelian Ilie
A Systematic Review on the Occurrence of <i>Babesia</i> spp. and <i>Anaplasma</i> spp. in Ticks and Wild Boar from Europe—A 15-Year Retrospective Study
Pathogens
<i>Babesia</i> spp.
<i>Anaplasma</i> spp.
wild boar
tick-borne pathogens
zoonotic diseases
Europe
title A Systematic Review on the Occurrence of <i>Babesia</i> spp. and <i>Anaplasma</i> spp. in Ticks and Wild Boar from Europe—A 15-Year Retrospective Study
title_full A Systematic Review on the Occurrence of <i>Babesia</i> spp. and <i>Anaplasma</i> spp. in Ticks and Wild Boar from Europe—A 15-Year Retrospective Study
title_fullStr A Systematic Review on the Occurrence of <i>Babesia</i> spp. and <i>Anaplasma</i> spp. in Ticks and Wild Boar from Europe—A 15-Year Retrospective Study
title_full_unstemmed A Systematic Review on the Occurrence of <i>Babesia</i> spp. and <i>Anaplasma</i> spp. in Ticks and Wild Boar from Europe—A 15-Year Retrospective Study
title_short A Systematic Review on the Occurrence of <i>Babesia</i> spp. and <i>Anaplasma</i> spp. in Ticks and Wild Boar from Europe—A 15-Year Retrospective Study
title_sort systematic review on the occurrence of i babesia i spp and i anaplasma i spp in ticks and wild boar from europe a 15 year retrospective study
topic <i>Babesia</i> spp.
<i>Anaplasma</i> spp.
wild boar
tick-borne pathogens
zoonotic diseases
Europe
url https://www.mdpi.com/2076-0817/14/7/612
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