Wernicke encephalopathy in a patient with drug-induced liver failure: a case report
IntroductionWernicke encephalopathy is a metabolic disease mainly associated with vitamin B1 deficiency, which is common in chronic alcoholism. Non-alcoholic Wernicke encephalopathy is difficult for early diagnosis.Case presentationOne case involved a 62-year-old man who was admitted to hospital wit...
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| Format: | Article |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2024.1505974/full |
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| author | Jiao-Jiao Cao Jing Li Yan Cheng Li-Min Luo Yang Chen Chang-Xing Huang Ye Zhang |
| author_facet | Jiao-Jiao Cao Jing Li Yan Cheng Li-Min Luo Yang Chen Chang-Xing Huang Ye Zhang |
| author_sort | Jiao-Jiao Cao |
| collection | DOAJ |
| description | IntroductionWernicke encephalopathy is a metabolic disease mainly associated with vitamin B1 deficiency, which is common in chronic alcoholism. Non-alcoholic Wernicke encephalopathy is difficult for early diagnosis.Case presentationOne case involved a 62-year-old man who was admitted to hospital with drug-induced liver failure. He presented lower extremity weakness and progressive worsening of consciousness disturbance post-admission and was eventually identified as Wernicke encephalopathy by magnetic resonance imaging scan and deficiency in vitamin B1. The classic symmetric hyperintense signals on T2-weighted and diffusion-weighted images were reversible after intravenous vitamin B1 supplementation.ConclusionA high index of clinical suspicion is required for early diagnosis and appropriate preventive and therapeutic strategies by adequate and immediate vitamin B1 supplements in the reversible stage of Wernicke encephalopathy. |
| format | Article |
| id | doaj-art-d70e097328024295a9473df06cf6cb29 |
| institution | Kabale University |
| issn | 2296-861X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj-art-d70e097328024295a9473df06cf6cb292025-01-07T06:40:38ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2025-01-011110.3389/fnut.2024.15059741505974Wernicke encephalopathy in a patient with drug-induced liver failure: a case reportJiao-Jiao Cao0Jing Li1Yan Cheng2Li-Min Luo3Yang Chen4Chang-Xing Huang5Ye Zhang6Department of Infectious Diseases, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi, ChinaDepartment of Infectious Diseases, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi, ChinaDepartment of Infectious Diseases, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi, ChinaDepartment of Infectious Diseases, Air Force Hospital of Southern Theatre Command, Guangzhou, Guangdong, ChinaSchool of Basic Medicine, Fourth Military Medical University, Xi'an, Shaanxi, ChinaDepartment of Infectious Diseases, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi, ChinaDepartment of Infectious Diseases, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi, ChinaIntroductionWernicke encephalopathy is a metabolic disease mainly associated with vitamin B1 deficiency, which is common in chronic alcoholism. Non-alcoholic Wernicke encephalopathy is difficult for early diagnosis.Case presentationOne case involved a 62-year-old man who was admitted to hospital with drug-induced liver failure. He presented lower extremity weakness and progressive worsening of consciousness disturbance post-admission and was eventually identified as Wernicke encephalopathy by magnetic resonance imaging scan and deficiency in vitamin B1. The classic symmetric hyperintense signals on T2-weighted and diffusion-weighted images were reversible after intravenous vitamin B1 supplementation.ConclusionA high index of clinical suspicion is required for early diagnosis and appropriate preventive and therapeutic strategies by adequate and immediate vitamin B1 supplements in the reversible stage of Wernicke encephalopathy.https://www.frontiersin.org/articles/10.3389/fnut.2024.1505974/fullWernicke encephalopathynon-alcoholicdrug-induced liver injuryliver failurevitamin B1 |
| spellingShingle | Jiao-Jiao Cao Jing Li Yan Cheng Li-Min Luo Yang Chen Chang-Xing Huang Ye Zhang Wernicke encephalopathy in a patient with drug-induced liver failure: a case report Frontiers in Nutrition Wernicke encephalopathy non-alcoholic drug-induced liver injury liver failure vitamin B1 |
| title | Wernicke encephalopathy in a patient with drug-induced liver failure: a case report |
| title_full | Wernicke encephalopathy in a patient with drug-induced liver failure: a case report |
| title_fullStr | Wernicke encephalopathy in a patient with drug-induced liver failure: a case report |
| title_full_unstemmed | Wernicke encephalopathy in a patient with drug-induced liver failure: a case report |
| title_short | Wernicke encephalopathy in a patient with drug-induced liver failure: a case report |
| title_sort | wernicke encephalopathy in a patient with drug induced liver failure a case report |
| topic | Wernicke encephalopathy non-alcoholic drug-induced liver injury liver failure vitamin B1 |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2024.1505974/full |
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