Treatment Adherence among People with Drug-resistant Tuberculosis in Lagos Nigeria: The Effects of Stigma, Resilience, Social Support, and Temporal Discounting

Background: This study assessed the effects of social support, resilience, temporal discounting, and stigma on medication adherence among people with drug-resistant tuberculosis (PwDR-TB) in Lagos, Nigeria. Methods: A cross-sectional study was conducted between September and December 2023 among 203...

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Main Authors: Olusola Adedeji Adejumo, Olusoji James Daniel, Champaklal Jinabhai, Firoza Haffejee
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:International Journal of Mycobacteriology
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Online Access:https://journals.lww.com/10.4103/ijmy.ijmy_209_24
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author Olusola Adedeji Adejumo
Olusoji James Daniel
Champaklal Jinabhai
Firoza Haffejee
author_facet Olusola Adedeji Adejumo
Olusoji James Daniel
Champaklal Jinabhai
Firoza Haffejee
author_sort Olusola Adedeji Adejumo
collection DOAJ
description Background: This study assessed the effects of social support, resilience, temporal discounting, and stigma on medication adherence among people with drug-resistant tuberculosis (PwDR-TB) in Lagos, Nigeria. Methods: A cross-sectional study was conducted between September and December 2023 among 203 adults on DR-TB treatment. The Morisky Medication Adherence Scale-8, Redwood DR-TB scale, multidimensional scale of perceived social support, brief resilience scale, and deferment of gratification scale were used to assess adherence, stigma, social support, resilience, and temporal discounting respectively. Pearson’s correlation and hierarchical linear regression analysis were conducted to explore the relationships between adherence, stigma, social support, resilience, and temporal discounting. Results: The prevalence of low, medium, and high adherence was 20.7%, 73.4%, and 5.9%, respectively. Adherence was positively associated with social support (B = 0.380, P < 0.001), resilience (B = 0.210, P < 0.001), and temporal discounting (B = 0.364, 0 < 0.001) and negatively associated with stigma (B = −0.317, P < 0.001). Temporal discounting made a higher significant contribution (B = 0.343, P < 0.001) in predicting adherence than social support (B = 0.187, P = 0.005), resilience (B = 0.175, P = 0.002) and stigma (B = −0.317, P < 0.001). Conclusion: Patient-centred interventions that promote social support, resilience, and temporal discounting are urgently needed to enhance adherence among PwDR-TB. Stigma reduction strategies are required at all levels.
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spelling doaj-art-d70de3d3ac424de2ba2ffce95e4d16f32025-08-20T01:53:00ZengWolters Kluwer Medknow PublicationsInternational Journal of Mycobacteriology2212-55312212-554X2025-01-01141364210.4103/ijmy.ijmy_209_24Treatment Adherence among People with Drug-resistant Tuberculosis in Lagos Nigeria: The Effects of Stigma, Resilience, Social Support, and Temporal DiscountingOlusola Adedeji AdejumoOlusoji James DanielChampaklal JinabhaiFiroza HaffejeeBackground: This study assessed the effects of social support, resilience, temporal discounting, and stigma on medication adherence among people with drug-resistant tuberculosis (PwDR-TB) in Lagos, Nigeria. Methods: A cross-sectional study was conducted between September and December 2023 among 203 adults on DR-TB treatment. The Morisky Medication Adherence Scale-8, Redwood DR-TB scale, multidimensional scale of perceived social support, brief resilience scale, and deferment of gratification scale were used to assess adherence, stigma, social support, resilience, and temporal discounting respectively. Pearson’s correlation and hierarchical linear regression analysis were conducted to explore the relationships between adherence, stigma, social support, resilience, and temporal discounting. Results: The prevalence of low, medium, and high adherence was 20.7%, 73.4%, and 5.9%, respectively. Adherence was positively associated with social support (B = 0.380, P < 0.001), resilience (B = 0.210, P < 0.001), and temporal discounting (B = 0.364, 0 < 0.001) and negatively associated with stigma (B = −0.317, P < 0.001). Temporal discounting made a higher significant contribution (B = 0.343, P < 0.001) in predicting adherence than social support (B = 0.187, P = 0.005), resilience (B = 0.175, P = 0.002) and stigma (B = −0.317, P < 0.001). Conclusion: Patient-centred interventions that promote social support, resilience, and temporal discounting are urgently needed to enhance adherence among PwDR-TB. Stigma reduction strategies are required at all levels.https://journals.lww.com/10.4103/ijmy.ijmy_209_24adherencedrug-resistant tuberculosisresiliencesocial supportstigmatemporal discounting
spellingShingle Olusola Adedeji Adejumo
Olusoji James Daniel
Champaklal Jinabhai
Firoza Haffejee
Treatment Adherence among People with Drug-resistant Tuberculosis in Lagos Nigeria: The Effects of Stigma, Resilience, Social Support, and Temporal Discounting
International Journal of Mycobacteriology
adherence
drug-resistant tuberculosis
resilience
social support
stigma
temporal discounting
title Treatment Adherence among People with Drug-resistant Tuberculosis in Lagos Nigeria: The Effects of Stigma, Resilience, Social Support, and Temporal Discounting
title_full Treatment Adherence among People with Drug-resistant Tuberculosis in Lagos Nigeria: The Effects of Stigma, Resilience, Social Support, and Temporal Discounting
title_fullStr Treatment Adherence among People with Drug-resistant Tuberculosis in Lagos Nigeria: The Effects of Stigma, Resilience, Social Support, and Temporal Discounting
title_full_unstemmed Treatment Adherence among People with Drug-resistant Tuberculosis in Lagos Nigeria: The Effects of Stigma, Resilience, Social Support, and Temporal Discounting
title_short Treatment Adherence among People with Drug-resistant Tuberculosis in Lagos Nigeria: The Effects of Stigma, Resilience, Social Support, and Temporal Discounting
title_sort treatment adherence among people with drug resistant tuberculosis in lagos nigeria the effects of stigma resilience social support and temporal discounting
topic adherence
drug-resistant tuberculosis
resilience
social support
stigma
temporal discounting
url https://journals.lww.com/10.4103/ijmy.ijmy_209_24
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