Prevalence of abnormal seminal fluid and associated factors among patients attending fertility clinics in Osogbo: a cross-sectional study

Background: Infertility is a global health issue affecting millions of couples worldwide. In Nigeria, the prevalence of infertility is particularly high, underscoring the need for a better understanding of the factors contributing to male infertility, with Seminal Fluid Analysis (SFA) being a cr...

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Main Authors: Kehinde Awodele, Sunday Charles Adeyemo, Eniola Dorcas Olabode, Adeniyi Olanipekun Fasanu, Lanre Olaitan, Akintunde Rasaq Akindele, Funso Abidemi Olagunju, Adeola Dorcas Aderinwale
Format: Article
Language:English
Published: MRE Press 2025-03-01
Series:Journal of Men's Health
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Online Access:https://oss.jomh.org/files/article/20250328-510/pdf/JOMH2024080905.pdf
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author Kehinde Awodele
Sunday Charles Adeyemo
Eniola Dorcas Olabode
Adeniyi Olanipekun Fasanu
Lanre Olaitan
Akintunde Rasaq Akindele
Funso Abidemi Olagunju
Adeola Dorcas Aderinwale
author_facet Kehinde Awodele
Sunday Charles Adeyemo
Eniola Dorcas Olabode
Adeniyi Olanipekun Fasanu
Lanre Olaitan
Akintunde Rasaq Akindele
Funso Abidemi Olagunju
Adeola Dorcas Aderinwale
author_sort Kehinde Awodele
collection DOAJ
description Background: Infertility is a global health issue affecting millions of couples worldwide. In Nigeria, the prevalence of infertility is particularly high, underscoring the need for a better understanding of the factors contributing to male infertility, with Seminal Fluid Analysis (SFA) being a critical diagnostic tool. This study aimed to assess the prevalence of abnormal seminal fluid and its associated factors among patients attending fertility clinics in Osogbo, Nigeria. Methods: A descriptive cross-sectional study design was used among male patients attending fertility centers in Osogbo, Osun State. Fisher’s formula (n = z2pq/d2) was used to determine the sample size, and 305 respondents were selected using a multistage sampling technique. A pre-tested questionnaire was used to collect data from respondents, and those who consented to participate underwent SFA. Data were analyzed using IBM Statistical Product for Service Solution (SPSS) version 27. Descriptive statistics were performed for all variables, while bivariate and multivariate analyses were conducted at a significance level of p < 0.05. Results: The majority of the respondents, 257 (84.3%), had at least one abnormality in their seminal fluid. Multiple regression analysis revealed that habitual drunkards were approximately five times more likely to have at least one abnormality in their seminal fluid (Odd’s ratio (OR): 4.990, p: 0.004, Confidence Interval (CI): 1.688–14.749), while smokers were three times more likely to have at least one abnormality in their seminal fluid (p = 0.005, OR = 3.300 and CI = 1.396–4.273). Additionally, respondents with a history of sexually transmitted infections were 3.5 times more likely to have at least one abnormality in their seminal fluid (p = 0.039, OR = 3.595 and CI = 1.072–14.146). Conclusions: This study observed a high prevalence of abnormal seminal fluid, which was significantly associated with lifestyle habits such as smoking and alcohol consumption, as well as a history of sexually transmitted infection.
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spelling doaj-art-d70d7f74e55b433a8be305cbaf3e3da62025-08-20T03:09:41ZengMRE PressJournal of Men's Health1875-68671875-68592025-03-01213606510.22514/jomh.2025.037S1875-6867(25)00354-9Prevalence of abnormal seminal fluid and associated factors among patients attending fertility clinics in Osogbo: a cross-sectional studyKehinde Awodele0Sunday Charles Adeyemo1Eniola Dorcas Olabode2Adeniyi Olanipekun Fasanu3Lanre Olaitan4Akintunde Rasaq Akindele5Funso Abidemi Olagunju6Adeola Dorcas Aderinwale7Obstetrics and Gynecology Department, Osun State University, 230001 Osogbo, OS, NigeriaInstitut Superieur de Sante, 8000 Niamey, Niger RepublicDepartment of Community Health, Obafemi Awolowo University, 220001 Ile-Ife, OS, NigeriaObstetrics and Gynecology Department, Osun State University, 230001 Osogbo, OS, NigeriaDepartment of Public Health, University of Ilorin, 240101 Ilorin, KWA, NigeriaObstetrics and Gynecology Department, Osun State University, 230001 Osogbo, OS, NigeriaObstetrics and Gynecology Department, Osun State University, 230001 Osogbo, OS, NigeriaDepartment of Public Health, Adeleke University, 232101 Ede, OS, NigeriaBackground: Infertility is a global health issue affecting millions of couples worldwide. In Nigeria, the prevalence of infertility is particularly high, underscoring the need for a better understanding of the factors contributing to male infertility, with Seminal Fluid Analysis (SFA) being a critical diagnostic tool. This study aimed to assess the prevalence of abnormal seminal fluid and its associated factors among patients attending fertility clinics in Osogbo, Nigeria. Methods: A descriptive cross-sectional study design was used among male patients attending fertility centers in Osogbo, Osun State. Fisher’s formula (n = z2pq/d2) was used to determine the sample size, and 305 respondents were selected using a multistage sampling technique. A pre-tested questionnaire was used to collect data from respondents, and those who consented to participate underwent SFA. Data were analyzed using IBM Statistical Product for Service Solution (SPSS) version 27. Descriptive statistics were performed for all variables, while bivariate and multivariate analyses were conducted at a significance level of p < 0.05. Results: The majority of the respondents, 257 (84.3%), had at least one abnormality in their seminal fluid. Multiple regression analysis revealed that habitual drunkards were approximately five times more likely to have at least one abnormality in their seminal fluid (Odd’s ratio (OR): 4.990, p: 0.004, Confidence Interval (CI): 1.688–14.749), while smokers were three times more likely to have at least one abnormality in their seminal fluid (p = 0.005, OR = 3.300 and CI = 1.396–4.273). Additionally, respondents with a history of sexually transmitted infections were 3.5 times more likely to have at least one abnormality in their seminal fluid (p = 0.039, OR = 3.595 and CI = 1.072–14.146). Conclusions: This study observed a high prevalence of abnormal seminal fluid, which was significantly associated with lifestyle habits such as smoking and alcohol consumption, as well as a history of sexually transmitted infection.https://oss.jomh.org/files/article/20250328-510/pdf/JOMH2024080905.pdfmale infertilityimplicationsseminal fluid analysissperm count
spellingShingle Kehinde Awodele
Sunday Charles Adeyemo
Eniola Dorcas Olabode
Adeniyi Olanipekun Fasanu
Lanre Olaitan
Akintunde Rasaq Akindele
Funso Abidemi Olagunju
Adeola Dorcas Aderinwale
Prevalence of abnormal seminal fluid and associated factors among patients attending fertility clinics in Osogbo: a cross-sectional study
Journal of Men's Health
male infertility
implications
seminal fluid analysis
sperm count
title Prevalence of abnormal seminal fluid and associated factors among patients attending fertility clinics in Osogbo: a cross-sectional study
title_full Prevalence of abnormal seminal fluid and associated factors among patients attending fertility clinics in Osogbo: a cross-sectional study
title_fullStr Prevalence of abnormal seminal fluid and associated factors among patients attending fertility clinics in Osogbo: a cross-sectional study
title_full_unstemmed Prevalence of abnormal seminal fluid and associated factors among patients attending fertility clinics in Osogbo: a cross-sectional study
title_short Prevalence of abnormal seminal fluid and associated factors among patients attending fertility clinics in Osogbo: a cross-sectional study
title_sort prevalence of abnormal seminal fluid and associated factors among patients attending fertility clinics in osogbo a cross sectional study
topic male infertility
implications
seminal fluid analysis
sperm count
url https://oss.jomh.org/files/article/20250328-510/pdf/JOMH2024080905.pdf
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