Implications of Heart Failure Treatment on Atrial Fibrillation Onset: A Retrospective Study
<i>Background and Objectives</i>: Atrial fibrillation (AF) is one of the most common supraventricular arrhythmias in the adult population worldwide and it is frequently associated with heart failure (HF). The coexistence of these conditions increases morbidity, mortality and reduces qual...
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MDPI AG
2025-02-01
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| Online Access: | https://www.mdpi.com/1648-9144/61/3/414 |
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| author | Loredana Suhov Adrian Apostol Larissa Dăniluc Lina Haj Ali Oana Elena Sandu Carina Bogdan Minodora Andor |
| author_facet | Loredana Suhov Adrian Apostol Larissa Dăniluc Lina Haj Ali Oana Elena Sandu Carina Bogdan Minodora Andor |
| author_sort | Loredana Suhov |
| collection | DOAJ |
| description | <i>Background and Objectives</i>: Atrial fibrillation (AF) is one of the most common supraventricular arrhythmias in the adult population worldwide and it is frequently associated with heart failure (HF). The coexistence of these conditions increases morbidity, mortality and reduces quality of life in these patients. Therefore, it is important to delay the onset of AF in HF patients in order to avoid complications. The study aims to assess whether HF treatment influences AF onset. <i>Materials and Methods</i>: This retrospective observational study included 260 patients, 144 patients with heart failure treated with sodium–glucose cotransporter 2 inhibitors (SGLT2i) and 116 patients with heart failure without SGLT2i treatment (control group) hospitalized at least twice in the Cardiology Department of the “Pius Brinzeu” Emergency County Hospital between 2022 and 2024. <i>Results</i>: Treatment with SGLT2i was associated with a lower prevalence of atrial fibrillation in patients with heart failure. <i>Conclusions</i>: The study highlights the cardiovascular benefits of SGLT2 inhibitors and suggests a potential effect on the onset of AF in heart failure patients. |
| format | Article |
| id | doaj-art-d6fdcaf487364b039b3b0ba087ea1796 |
| institution | OA Journals |
| issn | 1010-660X 1648-9144 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj-art-d6fdcaf487364b039b3b0ba087ea17962025-08-20T02:11:08ZengMDPI AGMedicina1010-660X1648-91442025-02-0161341410.3390/medicina61030414Implications of Heart Failure Treatment on Atrial Fibrillation Onset: A Retrospective StudyLoredana Suhov0Adrian Apostol1Larissa Dăniluc2Lina Haj Ali3Oana Elena Sandu4Carina Bogdan5Minodora Andor6Doctoral School, “Victor Babes” University of Medicine and Pharmacy, Eftimie Murgu Sq. No. 2, 300041 Timisoara, RomaniaDepartment of Cardiology, Pius Brinzeu Clinical Emergency County Hospital Timisoara, 300736 Timisoara, RomaniaDoctoral School, “Victor Babes” University of Medicine and Pharmacy, Eftimie Murgu Sq. No. 2, 300041 Timisoara, RomaniaDoctoral School, “Victor Babes” University of Medicine and Pharmacy, Eftimie Murgu Sq. No. 2, 300041 Timisoara, RomaniaDoctoral School, “Victor Babes” University of Medicine and Pharmacy, Eftimie Murgu Sq. No. 2, 300041 Timisoara, RomaniaDoctoral School, “Victor Babes” University of Medicine and Pharmacy, Eftimie Murgu Sq. No. 2, 300041 Timisoara, RomaniaDepartment V, Internal Medicine I, Discipline of Medical Semiotics II, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, Romania<i>Background and Objectives</i>: Atrial fibrillation (AF) is one of the most common supraventricular arrhythmias in the adult population worldwide and it is frequently associated with heart failure (HF). The coexistence of these conditions increases morbidity, mortality and reduces quality of life in these patients. Therefore, it is important to delay the onset of AF in HF patients in order to avoid complications. The study aims to assess whether HF treatment influences AF onset. <i>Materials and Methods</i>: This retrospective observational study included 260 patients, 144 patients with heart failure treated with sodium–glucose cotransporter 2 inhibitors (SGLT2i) and 116 patients with heart failure without SGLT2i treatment (control group) hospitalized at least twice in the Cardiology Department of the “Pius Brinzeu” Emergency County Hospital between 2022 and 2024. <i>Results</i>: Treatment with SGLT2i was associated with a lower prevalence of atrial fibrillation in patients with heart failure. <i>Conclusions</i>: The study highlights the cardiovascular benefits of SGLT2 inhibitors and suggests a potential effect on the onset of AF in heart failure patients.https://www.mdpi.com/1648-9144/61/3/414atrial fibrillationheart failureejection fractionSGLT-2 inhibitors |
| spellingShingle | Loredana Suhov Adrian Apostol Larissa Dăniluc Lina Haj Ali Oana Elena Sandu Carina Bogdan Minodora Andor Implications of Heart Failure Treatment on Atrial Fibrillation Onset: A Retrospective Study Medicina atrial fibrillation heart failure ejection fraction SGLT-2 inhibitors |
| title | Implications of Heart Failure Treatment on Atrial Fibrillation Onset: A Retrospective Study |
| title_full | Implications of Heart Failure Treatment on Atrial Fibrillation Onset: A Retrospective Study |
| title_fullStr | Implications of Heart Failure Treatment on Atrial Fibrillation Onset: A Retrospective Study |
| title_full_unstemmed | Implications of Heart Failure Treatment on Atrial Fibrillation Onset: A Retrospective Study |
| title_short | Implications of Heart Failure Treatment on Atrial Fibrillation Onset: A Retrospective Study |
| title_sort | implications of heart failure treatment on atrial fibrillation onset a retrospective study |
| topic | atrial fibrillation heart failure ejection fraction SGLT-2 inhibitors |
| url | https://www.mdpi.com/1648-9144/61/3/414 |
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