CXCL8 is essential for cervical cancer cell acquired radioresistance and acts as a promising therapeutic target in cervical cancer

CXCL8 is essential for cervical cancer cell acquired radioresistance and acts as a promising therapeutic target in cervical cancer

Abstract Acquired radioresistance critically challenges cervical cancer radiotherapy management. Clinically relevant radioresistant cell models remain scarce, and CXCL8’s role in cervical cancer—despite its tumorigenic/therapy-resistant associations in other cancers—is poorly characterized. Two radi...

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Bibliographic Details
Main Authors: Qinghong Hu, Xiaoxiao Zuo, Xiaobin Gu, Liya Liu, Ying Tang, Xiaomin Niu, Yonggang Shi, Liping Han
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Cervical cancer
Radioresistance
CXCL8
Radiosensitization
Tumor microenvironment
Online Access:https://doi.org/10.1038/s41598-025-05435-w
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