Levels and health effects of maternal and infant exposure to chlorinated polyfluorinated ether sulfonic acid
Chlorinated polyfluoroalkyl ether sulfonic acid (Cl-PFESA, trade name F-53B), a substitute for perfluorooctane sulfonate (PFOS), notably featuring 6:2 Cl-PFESA and 8:2 Cl-PFESA as its primary components, are the most biologically persistent per-and polyfluoroalkyl substances (PFAS) currently known....
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| Format: | Article |
| Language: | English |
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Editorial Committee of Journal of Environmental and Occupational Medicine
2024-12-01
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| Series: | 环境与职业医学 |
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| Online Access: | http://www.jeom.org/article/cn/10.11836/JEOM24248 |
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| author | Yujie CAO Ying TIAN Yu GAO |
| author_facet | Yujie CAO Ying TIAN Yu GAO |
| author_sort | Yujie CAO |
| collection | DOAJ |
| description | Chlorinated polyfluoroalkyl ether sulfonic acid (Cl-PFESA, trade name F-53B), a substitute for perfluorooctane sulfonate (PFOS), notably featuring 6:2 Cl-PFESA and 8:2 Cl-PFESA as its primary components, are the most biologically persistent per-and polyfluoroalkyl substances (PFAS) currently known. Since its initial synthesis in China in 1975, F-53B has served as an antifogging agent in the electroplating industry for over four decades. Recently, F-53B has been detected across various matrix and human samples, ranking among the top three PFAS concentrations in maternal and umbilical cord blood sera in China, according to available epidemiological studies. Current limited epidemiological studies indicate that F-53B poses multiple adverse effects on maternal and infant health. Therefore, this article reviewed the exposure levels of F-53B in mothers and infants, along with its adverse health effects, thereby providing insights for evaluating the toxic effects of F-53B on maternal and infant health and establishing safety thresholds. |
| format | Article |
| id | doaj-art-d6f344bc9a3849c6a9046e2033789c16 |
| institution | Kabale University |
| issn | 2095-9982 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Editorial Committee of Journal of Environmental and Occupational Medicine |
| record_format | Article |
| series | 环境与职业医学 |
| spelling | doaj-art-d6f344bc9a3849c6a9046e2033789c162025-01-09T05:41:12ZengEditorial Committee of Journal of Environmental and Occupational Medicine环境与职业医学2095-99822024-12-0141121341134810.11836/JEOM2424824248Levels and health effects of maternal and infant exposure to chlorinated polyfluorinated ether sulfonic acidYujie CAO0Ying TIAN1Yu GAO2Department of Environmental Health, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, ChinaDepartment of Environmental Health, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, ChinaDepartment of Environmental Health, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, ChinaChlorinated polyfluoroalkyl ether sulfonic acid (Cl-PFESA, trade name F-53B), a substitute for perfluorooctane sulfonate (PFOS), notably featuring 6:2 Cl-PFESA and 8:2 Cl-PFESA as its primary components, are the most biologically persistent per-and polyfluoroalkyl substances (PFAS) currently known. Since its initial synthesis in China in 1975, F-53B has served as an antifogging agent in the electroplating industry for over four decades. Recently, F-53B has been detected across various matrix and human samples, ranking among the top three PFAS concentrations in maternal and umbilical cord blood sera in China, according to available epidemiological studies. Current limited epidemiological studies indicate that F-53B poses multiple adverse effects on maternal and infant health. Therefore, this article reviewed the exposure levels of F-53B in mothers and infants, along with its adverse health effects, thereby providing insights for evaluating the toxic effects of F-53B on maternal and infant health and establishing safety thresholds.http://www.jeom.org/article/cn/10.11836/JEOM24248per- and polyfluoroalkyl substanceschlorinated polyfluorinated ether sulfonic acid6:2 chlorinated polyfluorinated ether sulfonic acid8:2 chlorinated polyfluorinated ether sulfonic acidmaternal and infant health |
| spellingShingle | Yujie CAO Ying TIAN Yu GAO Levels and health effects of maternal and infant exposure to chlorinated polyfluorinated ether sulfonic acid 环境与职业医学 per- and polyfluoroalkyl substances chlorinated polyfluorinated ether sulfonic acid 6:2 chlorinated polyfluorinated ether sulfonic acid 8:2 chlorinated polyfluorinated ether sulfonic acid maternal and infant health |
| title | Levels and health effects of maternal and infant exposure to chlorinated polyfluorinated ether sulfonic acid |
| title_full | Levels and health effects of maternal and infant exposure to chlorinated polyfluorinated ether sulfonic acid |
| title_fullStr | Levels and health effects of maternal and infant exposure to chlorinated polyfluorinated ether sulfonic acid |
| title_full_unstemmed | Levels and health effects of maternal and infant exposure to chlorinated polyfluorinated ether sulfonic acid |
| title_short | Levels and health effects of maternal and infant exposure to chlorinated polyfluorinated ether sulfonic acid |
| title_sort | levels and health effects of maternal and infant exposure to chlorinated polyfluorinated ether sulfonic acid |
| topic | per- and polyfluoroalkyl substances chlorinated polyfluorinated ether sulfonic acid 6:2 chlorinated polyfluorinated ether sulfonic acid 8:2 chlorinated polyfluorinated ether sulfonic acid maternal and infant health |
| url | http://www.jeom.org/article/cn/10.11836/JEOM24248 |
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