Efficacy and safety of lateral approach laparoscopic spleen-preserving distal pancreatectomy: a multicenter retrospective cohort study
Abstract This study compared the lateral approach laparoscopic spleen-preserving distal pancreatectomy (LA LSPDP) with the conventional approach to LSPDP (CA LSPDP) for benign to borderline malignant tumors in the pancreatic tail. A multicenter retrospective cohort of patients undergoing LA LSPDP or...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-08-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-10997-w |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849237803646320640 |
|---|---|
| author | Sung Eun Park Tae Yoon Lee Young Chul Yoon Chang Ho Seo Gun Hyung Na Yun Kyoung Woo Dong Do You Tae Ho Hong |
| author_facet | Sung Eun Park Tae Yoon Lee Young Chul Yoon Chang Ho Seo Gun Hyung Na Yun Kyoung Woo Dong Do You Tae Ho Hong |
| author_sort | Sung Eun Park |
| collection | DOAJ |
| description | Abstract This study compared the lateral approach laparoscopic spleen-preserving distal pancreatectomy (LA LSPDP) with the conventional approach to LSPDP (CA LSPDP) for benign to borderline malignant tumors in the pancreatic tail. A multicenter retrospective cohort of patients undergoing LA LSPDP or CA LSPDP for pancreatic tail tumors with a tumor center located beyond the left lateral border of the aorta was analyzed. A 1:1 propensity score matching (PSM) yielded 56 patients per group. A total of 172 patients were planned for LSPDP. After PSM, the tumor sizes were comparable (3.1 cm vs 3.3 cm, p = 0.549). However, resected specimens were longer in the CA LSPDP group (8.4 cm vs. 7.7 cm, p < 0.001). Rates of conversion to open surgery, the use of Warshaw’s technique, and the need for combined splenectomy were not significantly different between the two groups. However, the LA LSPDP group had a shorter operation time (127.1 min vs. 161.1 min, p = 0.002) and less blood loss (106.2 cc vs. 291.4 cc, p = 0.001). The postoperative complication rates were similar (35.7% vs. 27.3%, p = 0.339). LA LSPDP is a safe and effective technique that reduces operative time and blood loss in pancreatic tail tumors; however, larger prospective studies are needed to confirm this finding. |
| format | Article |
| id | doaj-art-d6ee2bf9274e488483b3e54d880f506c |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-d6ee2bf9274e488483b3e54d880f506c2025-08-20T04:01:51ZengNature PortfolioScientific Reports2045-23222025-08-011511810.1038/s41598-025-10997-wEfficacy and safety of lateral approach laparoscopic spleen-preserving distal pancreatectomy: a multicenter retrospective cohort studySung Eun Park0Tae Yoon Lee1Young Chul Yoon2Chang Ho Seo3Gun Hyung Na4Yun Kyoung Woo5Dong Do You6Tae Ho Hong7Department of Hepato-Biliary and Pancreas Surgery, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of KoreaDepartment of Surgery, Incheon St. Mary’s Hospital, College of Medicine, The Catholic University of KoreaDepartment of Surgery, Incheon St. Mary’s Hospital, College of Medicine, The Catholic University of KoreaDepartment of Surgery, Bucheon St. Mary’s Hospital, College of Medicine, The Catholic University of KoreaDepartment of Surgery, Bucheon St. Mary’s Hospital, College of Medicine, The Catholic University of KoreaDepartment of Surgery, St. Vincent’s Hospital, College of Medicine, The Catholic University of KoreaDepartment of Surgery, St. Vincent’s Hospital, College of Medicine, The Catholic University of KoreaDepartment of Hepato-Biliary and Pancreas Surgery, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of KoreaAbstract This study compared the lateral approach laparoscopic spleen-preserving distal pancreatectomy (LA LSPDP) with the conventional approach to LSPDP (CA LSPDP) for benign to borderline malignant tumors in the pancreatic tail. A multicenter retrospective cohort of patients undergoing LA LSPDP or CA LSPDP for pancreatic tail tumors with a tumor center located beyond the left lateral border of the aorta was analyzed. A 1:1 propensity score matching (PSM) yielded 56 patients per group. A total of 172 patients were planned for LSPDP. After PSM, the tumor sizes were comparable (3.1 cm vs 3.3 cm, p = 0.549). However, resected specimens were longer in the CA LSPDP group (8.4 cm vs. 7.7 cm, p < 0.001). Rates of conversion to open surgery, the use of Warshaw’s technique, and the need for combined splenectomy were not significantly different between the two groups. However, the LA LSPDP group had a shorter operation time (127.1 min vs. 161.1 min, p = 0.002) and less blood loss (106.2 cc vs. 291.4 cc, p = 0.001). The postoperative complication rates were similar (35.7% vs. 27.3%, p = 0.339). LA LSPDP is a safe and effective technique that reduces operative time and blood loss in pancreatic tail tumors; however, larger prospective studies are needed to confirm this finding.https://doi.org/10.1038/s41598-025-10997-wLaparoscopyDistal pancreatectomySplenic vessel preservationLeft lateral approachPancreatic neoplasms |
| spellingShingle | Sung Eun Park Tae Yoon Lee Young Chul Yoon Chang Ho Seo Gun Hyung Na Yun Kyoung Woo Dong Do You Tae Ho Hong Efficacy and safety of lateral approach laparoscopic spleen-preserving distal pancreatectomy: a multicenter retrospective cohort study Scientific Reports Laparoscopy Distal pancreatectomy Splenic vessel preservation Left lateral approach Pancreatic neoplasms |
| title | Efficacy and safety of lateral approach laparoscopic spleen-preserving distal pancreatectomy: a multicenter retrospective cohort study |
| title_full | Efficacy and safety of lateral approach laparoscopic spleen-preserving distal pancreatectomy: a multicenter retrospective cohort study |
| title_fullStr | Efficacy and safety of lateral approach laparoscopic spleen-preserving distal pancreatectomy: a multicenter retrospective cohort study |
| title_full_unstemmed | Efficacy and safety of lateral approach laparoscopic spleen-preserving distal pancreatectomy: a multicenter retrospective cohort study |
| title_short | Efficacy and safety of lateral approach laparoscopic spleen-preserving distal pancreatectomy: a multicenter retrospective cohort study |
| title_sort | efficacy and safety of lateral approach laparoscopic spleen preserving distal pancreatectomy a multicenter retrospective cohort study |
| topic | Laparoscopy Distal pancreatectomy Splenic vessel preservation Left lateral approach Pancreatic neoplasms |
| url | https://doi.org/10.1038/s41598-025-10997-w |
| work_keys_str_mv | AT sungeunpark efficacyandsafetyoflateralapproachlaparoscopicspleenpreservingdistalpancreatectomyamulticenterretrospectivecohortstudy AT taeyoonlee efficacyandsafetyoflateralapproachlaparoscopicspleenpreservingdistalpancreatectomyamulticenterretrospectivecohortstudy AT youngchulyoon efficacyandsafetyoflateralapproachlaparoscopicspleenpreservingdistalpancreatectomyamulticenterretrospectivecohortstudy AT changhoseo efficacyandsafetyoflateralapproachlaparoscopicspleenpreservingdistalpancreatectomyamulticenterretrospectivecohortstudy AT gunhyungna efficacyandsafetyoflateralapproachlaparoscopicspleenpreservingdistalpancreatectomyamulticenterretrospectivecohortstudy AT yunkyoungwoo efficacyandsafetyoflateralapproachlaparoscopicspleenpreservingdistalpancreatectomyamulticenterretrospectivecohortstudy AT dongdoyou efficacyandsafetyoflateralapproachlaparoscopicspleenpreservingdistalpancreatectomyamulticenterretrospectivecohortstudy AT taehohong efficacyandsafetyoflateralapproachlaparoscopicspleenpreservingdistalpancreatectomyamulticenterretrospectivecohortstudy |