Advances in the scaffolds fabrication techniques using biocompatible polymers and their biomedical application: A technical and statistical review

With the advancement in tissue engineering, researchers are working hard on new techniques to fabricate more advanced scaffolds from biocompatible polymers with enhanced porosity, appropriate mechanical strength, diverse shapes and sizes for potential applications in biomedical field in general and...

Full description

Saved in:
Bibliographic Details
Main Authors: Adnan Haider, Sajjad Haider, Madhusudana Rao Kummara, Tahseen Kamal, Abdul-Aziz A Alghyamah, Faiza Jan Iftikhar, Bushra Bano, Naeem Khan, Mohammad Amjid Afridi, Sung Soo Han, Ali Alrahlah, Rawaiz Khan
Format: Article
Language:English
Published: Springer 2020-02-01
Series:Journal of Saudi Chemical Society
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610320300028
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849315928943099904
author Adnan Haider
Sajjad Haider
Madhusudana Rao Kummara
Tahseen Kamal
Abdul-Aziz A Alghyamah
Faiza Jan Iftikhar
Bushra Bano
Naeem Khan
Mohammad Amjid Afridi
Sung Soo Han
Ali Alrahlah
Rawaiz Khan
author_facet Adnan Haider
Sajjad Haider
Madhusudana Rao Kummara
Tahseen Kamal
Abdul-Aziz A Alghyamah
Faiza Jan Iftikhar
Bushra Bano
Naeem Khan
Mohammad Amjid Afridi
Sung Soo Han
Ali Alrahlah
Rawaiz Khan
author_sort Adnan Haider
collection DOAJ
description With the advancement in tissue engineering, researchers are working hard on new techniques to fabricate more advanced scaffolds from biocompatible polymers with enhanced porosity, appropriate mechanical strength, diverse shapes and sizes for potential applications in biomedical field in general and tissue engineering in particular. These techniques include electrospinning, solution blow spinning, centrifugal spinning, particulate leaching (salt leaching), freeze-drying, lithography, self-assembly, phase separation, gas foaming, melt molding, 3-D printing, fiber mesh and solvent casting. In this article we have summarized the scaffold’s fabrication techniques from biocompatible polymers that are reported so far, the recent advances in these techniques, characterization of the physicochemical properties of scaffolds and their potential applications in the biomedical field and tissue engineering. The article will help both newcomers and experts working in the biomedical implant fabrication to not only find their desired information in one document but also understand the fabrication techniques and the parameters that control the success of biocompatible polymeric scaffolds. Furthermore, a static analysis of the work published in all forms on the most innovative techniques is also presented. The data is taken from Scopus, restricting the search to biomedical fields and tissue engineering. Keywords: Biocompatible polymeric Scaffolds, Scaffolds fabrication techniques, Tissue engineering, Biomedical application
format Article
id doaj-art-d6eb559b0ca34ae5a45b1cb6115b948d
institution Kabale University
issn 1319-6103
language English
publishDate 2020-02-01
publisher Springer
record_format Article
series Journal of Saudi Chemical Society
spelling doaj-art-d6eb559b0ca34ae5a45b1cb6115b948d2025-08-20T03:52:00ZengSpringerJournal of Saudi Chemical Society1319-61032020-02-0124218621510.1016/j.jscs.2020.01.002Advances in the scaffolds fabrication techniques using biocompatible polymers and their biomedical application: A technical and statistical reviewAdnan Haider0Sajjad Haider1Madhusudana Rao Kummara2Tahseen Kamal3Abdul-Aziz A Alghyamah4Faiza Jan Iftikhar5Bushra Bano6Naeem Khan7Mohammad Amjid Afridi8Sung Soo Han9Ali Alrahlah10Rawaiz Khan11Department of Chemistry, Kohat University of Science and Technology, Kohat 26000, KP, Pakistan; Department of Nano, Medical and Polymer Materials, College of Engineering, Yeungnam University, 280 Daehak-Ro, Gyeongsan 712-749, South KoreaDepartment of Chemical Engineering, College of Engineering, King Saud University, P.O BOX 800, Riyadh 11421, KSA, Saudi Arabia; Corresponding authors.Department of Nano, Medical and Polymer Materials, College of Engineering, Yeungnam University, 280 Daehak-Ro, Gyeongsan 712-749, South KoreaDepartment of Chemistry, Faculty of Science, King Abdul Aziz University, P.O. Box 80203, Jeddah 21589, Saudi ArabiaDepartment of Chemical Engineering, College of Engineering, King Saud University, P.O BOX 800, Riyadh 11421, KSA, Saudi ArabiaDepartment of Chemistry, Quaid Azam University, Islamabad, PakistanInstitute of Basic Medical Science, Khyber Medical University, Peshawar, KP, PakistanDepartment of Chemistry, Kohat University of Science and Technology, Kohat 26000, KP, PakistanDepartment of Pathology, Gajju Khan Medical College, Swab, KP, PakistanDepartment of Nano, Medical and Polymer Materials, College of Engineering, Yeungnam University, 280 Daehak-Ro, Gyeongsan 712-749, South Korea; Corresponding authors.Engineer Abdullah Bugshan Research Chair for Dental and Oral Rehabilitation, College of Dentistry, King Saud University, Riyadh 11545, Saudi Arabia; Restorative Dental Sciences Department, College of Dentistry, King Saud University, Riyadh 11545, Saudi ArabiaEngineer Abdullah Bugshan Research Chair for Dental and Oral Rehabilitation, College of Dentistry, King Saud University, Riyadh 11545, Saudi ArabiaWith the advancement in tissue engineering, researchers are working hard on new techniques to fabricate more advanced scaffolds from biocompatible polymers with enhanced porosity, appropriate mechanical strength, diverse shapes and sizes for potential applications in biomedical field in general and tissue engineering in particular. These techniques include electrospinning, solution blow spinning, centrifugal spinning, particulate leaching (salt leaching), freeze-drying, lithography, self-assembly, phase separation, gas foaming, melt molding, 3-D printing, fiber mesh and solvent casting. In this article we have summarized the scaffold’s fabrication techniques from biocompatible polymers that are reported so far, the recent advances in these techniques, characterization of the physicochemical properties of scaffolds and their potential applications in the biomedical field and tissue engineering. The article will help both newcomers and experts working in the biomedical implant fabrication to not only find their desired information in one document but also understand the fabrication techniques and the parameters that control the success of biocompatible polymeric scaffolds. Furthermore, a static analysis of the work published in all forms on the most innovative techniques is also presented. The data is taken from Scopus, restricting the search to biomedical fields and tissue engineering. Keywords: Biocompatible polymeric Scaffolds, Scaffolds fabrication techniques, Tissue engineering, Biomedical applicationhttp://www.sciencedirect.com/science/article/pii/S1319610320300028
spellingShingle Adnan Haider
Sajjad Haider
Madhusudana Rao Kummara
Tahseen Kamal
Abdul-Aziz A Alghyamah
Faiza Jan Iftikhar
Bushra Bano
Naeem Khan
Mohammad Amjid Afridi
Sung Soo Han
Ali Alrahlah
Rawaiz Khan
Advances in the scaffolds fabrication techniques using biocompatible polymers and their biomedical application: A technical and statistical review
Journal of Saudi Chemical Society
title Advances in the scaffolds fabrication techniques using biocompatible polymers and their biomedical application: A technical and statistical review
title_full Advances in the scaffolds fabrication techniques using biocompatible polymers and their biomedical application: A technical and statistical review
title_fullStr Advances in the scaffolds fabrication techniques using biocompatible polymers and their biomedical application: A technical and statistical review
title_full_unstemmed Advances in the scaffolds fabrication techniques using biocompatible polymers and their biomedical application: A technical and statistical review
title_short Advances in the scaffolds fabrication techniques using biocompatible polymers and their biomedical application: A technical and statistical review
title_sort advances in the scaffolds fabrication techniques using biocompatible polymers and their biomedical application a technical and statistical review
url http://www.sciencedirect.com/science/article/pii/S1319610320300028
work_keys_str_mv AT adnanhaider advancesinthescaffoldsfabricationtechniquesusingbiocompatiblepolymersandtheirbiomedicalapplicationatechnicalandstatisticalreview
AT sajjadhaider advancesinthescaffoldsfabricationtechniquesusingbiocompatiblepolymersandtheirbiomedicalapplicationatechnicalandstatisticalreview
AT madhusudanaraokummara advancesinthescaffoldsfabricationtechniquesusingbiocompatiblepolymersandtheirbiomedicalapplicationatechnicalandstatisticalreview
AT tahseenkamal advancesinthescaffoldsfabricationtechniquesusingbiocompatiblepolymersandtheirbiomedicalapplicationatechnicalandstatisticalreview
AT abdulazizaalghyamah advancesinthescaffoldsfabricationtechniquesusingbiocompatiblepolymersandtheirbiomedicalapplicationatechnicalandstatisticalreview
AT faizajaniftikhar advancesinthescaffoldsfabricationtechniquesusingbiocompatiblepolymersandtheirbiomedicalapplicationatechnicalandstatisticalreview
AT bushrabano advancesinthescaffoldsfabricationtechniquesusingbiocompatiblepolymersandtheirbiomedicalapplicationatechnicalandstatisticalreview
AT naeemkhan advancesinthescaffoldsfabricationtechniquesusingbiocompatiblepolymersandtheirbiomedicalapplicationatechnicalandstatisticalreview
AT mohammadamjidafridi advancesinthescaffoldsfabricationtechniquesusingbiocompatiblepolymersandtheirbiomedicalapplicationatechnicalandstatisticalreview
AT sungsoohan advancesinthescaffoldsfabricationtechniquesusingbiocompatiblepolymersandtheirbiomedicalapplicationatechnicalandstatisticalreview
AT alialrahlah advancesinthescaffoldsfabricationtechniquesusingbiocompatiblepolymersandtheirbiomedicalapplicationatechnicalandstatisticalreview
AT rawaizkhan advancesinthescaffoldsfabricationtechniquesusingbiocompatiblepolymersandtheirbiomedicalapplicationatechnicalandstatisticalreview