Skeletal muscle stem cells modulate niche function in Duchenne muscular dystrophy mouse through YY1-CCL5 axis

Skeletal muscle stem cells modulate niche function in Duchenne muscular dystrophy mouse through YY1-CCL5 axis

Abstract Adult skeletal muscle stem cells (MuSCs) are indispensable for muscle regeneration and tightly regulated by macrophages (MPs) and fibro-adipogenic progenitors (FAPs) in their niche. Deregulated MuSC/MP/FAP interactions and the ensuing inflammation and fibrosis are hallmarks of dystrophic mu...

Full description

Saved in:
Bibliographic Details
Main Authors: Yang Li, Chuhan Li, Qiang Sun, Xingyuan Liu, Fengyuan Chen, Yeelo Cheung, Yu Zhao, Ting Xie, Bénédicte Chazaud, Hao Sun, Huating Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56474-w
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items