A comprehensive study of AAV tropism across C57BL/6 mice, BALB/c mice, and crab-eating macaques

A comprehensive study of AAV tropism across C57BL/6 mice, BALB/c mice, and crab-eating macaques

Recombinant adeno-associated viruses (AAVs) have been widely used for gene delivery and gene therapy. However, certain AAV serotypes exhibited distinct transduction patterns among different mouse strains or between mice and non-human primates (NHPs). These variations prompted us to investigate the A...

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Bibliographic Details
Main Authors:	Kailun Fang, Xiali Yang, Yuanhua Liu, Junhui Xia, Ruoxi Wu, Fan Yang, Canbin Feng, Xinyu Liu, Linyu Shi, Guannan Geng, Hui Yang
Format:	Article
Language:	English
Published:	Elsevier 2025-03-01
Series:	Molecular Therapy: Methods & Clinical Development
Subjects:	AAV tropism AAV vector biodistribution AAV transduction C57BL/6 mice BALB/c mice crab-eating macaques
Online Access:	http://www.sciencedirect.com/science/article/pii/S2329050125000294
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