Poor hypotheses and research waste in biology: learning from a theory crisis in psychology
Abstract While psychologists have extensively discussed the notion of a “theory crisis” arising from vague and incorrect hypotheses, there has been no debate about such a crisis in biology. However, biologists have long discussed communication failures between theoreticians and empiricists. We argue...
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Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-02-01
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Series: | BMC Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12915-025-02134-w |
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Summary: | Abstract While psychologists have extensively discussed the notion of a “theory crisis” arising from vague and incorrect hypotheses, there has been no debate about such a crisis in biology. However, biologists have long discussed communication failures between theoreticians and empiricists. We argue such failure is one aspect of a theory crisis because misapplied and misunderstood theories lead to poor hypotheses and research waste. We review its solutions and compare them with methodology-focused solutions proposed for replication crises. We conclude by discussing how promoting inclusion, diversity, equity, and accessibility (IDEA) in theoretical biology could contribute to ameliorating breakdowns in the theory-empirical cycle. |
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ISSN: | 1741-7007 |