Step up to triple therapy versus switch to dual bronchodilator therapy in patients with COPD on an inhaled corticosteroid/long-acting β2-agonist: post-hoc analyses of KRONOS

Step up to triple therapy versus switch to dual bronchodilator therapy in patients with COPD on an inhaled corticosteroid/long-acting β2-agonist: post-hoc analyses of KRONOS

Abstract Background In people with chronic obstructive pulmonary disease (COPD) on inhaled corticosteroid/long-acting β2-agonist (ICS/LABA) therapy, the Global Initiative for Chronic Obstructive Lung Disease (GOLD) recommends stepping up to ICS/long-acting muscarinic antagonist (LAMA)/long-acting β2...

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Bibliographic Details
Main Authors: Dave Singh, Mona Bafadhel, Niki Arya, Jonathan Marshall, Himanshu Parikh, Dobrawa Kisielewicz, Charlotta Movitz, Karin Bowen, Mehul Patel
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Respiratory Research
Subjects:
Chronic obstructive pulmonary disease
Exacerbations
Lung function
Triple therapy
Online Access:https://doi.org/10.1186/s12931-025-03234-5
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