Parkinsonism Associated with Pathological 123I-FP-CIT SPECT (DaTSCAN) Results as the Initial Manifestation of Sporadic Creutzfeldt-Jakob Disease
Sporadic Creutzfeldt-Jakob disease (sCJD) is a type of progressive, subacute encephalopathy associated with spongiform degeneration of the central nervous system. sCJD includes a broad and heterogeneous spectrum of clinical variants, but extrapyramidal symptoms and signs at disease onset were rarely...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Neurological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2018/5157275 |
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| author | Sira Carrasco García de León Juan Pablo Cabello Ramón Ortiz Julia Vaamonde |
| author_facet | Sira Carrasco García de León Juan Pablo Cabello Ramón Ortiz Julia Vaamonde |
| author_sort | Sira Carrasco García de León |
| collection | DOAJ |
| description | Sporadic Creutzfeldt-Jakob disease (sCJD) is a type of progressive, subacute encephalopathy associated with spongiform degeneration of the central nervous system. sCJD includes a broad and heterogeneous spectrum of clinical variants, but extrapyramidal symptoms and signs at disease onset were rarely reported. We describe a case of unilateral parkinsonism associated with pathological 123I-ioflupane SPECT (DaTSCAN) results as the initial manifestation of M129V subtype sCJD patient. To the best of our knowledge, only 2 cases of Creutzfeldt-Jakob disease demonstrating nigrostriatal dopaminergic deficits in vivo using DaTSCAN have been published in the literature. |
| format | Article |
| id | doaj-art-d6c237775fcd42b9be69f2d73e25bc58 |
| institution | DOAJ |
| issn | 2090-6668 2090-6676 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Neurological Medicine |
| spelling | doaj-art-d6c237775fcd42b9be69f2d73e25bc582025-08-20T03:19:49ZengWileyCase Reports in Neurological Medicine2090-66682090-66762018-01-01201810.1155/2018/51572755157275Parkinsonism Associated with Pathological 123I-FP-CIT SPECT (DaTSCAN) Results as the Initial Manifestation of Sporadic Creutzfeldt-Jakob DiseaseSira Carrasco García de León0Juan Pablo Cabello1Ramón Ortiz2Julia Vaamonde3Department of Neurology, University General Hospital, Ciudad Real, SpainDepartment of Neurology, University General Hospital, Ciudad Real, SpainIntensive Care Unit, University General Hospital, Ciudad Real, SpainDepartment of Neurology, University General Hospital, Ciudad Real, SpainSporadic Creutzfeldt-Jakob disease (sCJD) is a type of progressive, subacute encephalopathy associated with spongiform degeneration of the central nervous system. sCJD includes a broad and heterogeneous spectrum of clinical variants, but extrapyramidal symptoms and signs at disease onset were rarely reported. We describe a case of unilateral parkinsonism associated with pathological 123I-ioflupane SPECT (DaTSCAN) results as the initial manifestation of M129V subtype sCJD patient. To the best of our knowledge, only 2 cases of Creutzfeldt-Jakob disease demonstrating nigrostriatal dopaminergic deficits in vivo using DaTSCAN have been published in the literature.http://dx.doi.org/10.1155/2018/5157275 |
| spellingShingle | Sira Carrasco García de León Juan Pablo Cabello Ramón Ortiz Julia Vaamonde Parkinsonism Associated with Pathological 123I-FP-CIT SPECT (DaTSCAN) Results as the Initial Manifestation of Sporadic Creutzfeldt-Jakob Disease Case Reports in Neurological Medicine |
| title | Parkinsonism Associated with Pathological 123I-FP-CIT SPECT (DaTSCAN) Results as the Initial Manifestation of Sporadic Creutzfeldt-Jakob Disease |
| title_full | Parkinsonism Associated with Pathological 123I-FP-CIT SPECT (DaTSCAN) Results as the Initial Manifestation of Sporadic Creutzfeldt-Jakob Disease |
| title_fullStr | Parkinsonism Associated with Pathological 123I-FP-CIT SPECT (DaTSCAN) Results as the Initial Manifestation of Sporadic Creutzfeldt-Jakob Disease |
| title_full_unstemmed | Parkinsonism Associated with Pathological 123I-FP-CIT SPECT (DaTSCAN) Results as the Initial Manifestation of Sporadic Creutzfeldt-Jakob Disease |
| title_short | Parkinsonism Associated with Pathological 123I-FP-CIT SPECT (DaTSCAN) Results as the Initial Manifestation of Sporadic Creutzfeldt-Jakob Disease |
| title_sort | parkinsonism associated with pathological 123i fp cit spect datscan results as the initial manifestation of sporadic creutzfeldt jakob disease |
| url | http://dx.doi.org/10.1155/2018/5157275 |
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