Insights into brain network dynamics across ages using group-ICA functional parcellation

Aging is a natural and inevitable process in human life that involves changes in the brain. The brain becomes structurally, functionally, and interconnected differently. The evolution of brain activity and its anatomy follows separate paths, causing them to not always align. Independent Component An...

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Main Authors: Lorena Malinalli López-Medina, Omar Paredes, Sorpresa Lora-Castro, Rebeca Romo-Vázquez, J. Alejandro Morales, Hugo Vélez-Pérez
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Franklin Open
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Online Access:http://www.sciencedirect.com/science/article/pii/S2773186324001087
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author Lorena Malinalli López-Medina
Omar Paredes
Sorpresa Lora-Castro
Rebeca Romo-Vázquez
J. Alejandro Morales
Hugo Vélez-Pérez
author_facet Lorena Malinalli López-Medina
Omar Paredes
Sorpresa Lora-Castro
Rebeca Romo-Vázquez
J. Alejandro Morales
Hugo Vélez-Pérez
author_sort Lorena Malinalli López-Medina
collection DOAJ
description Aging is a natural and inevitable process in human life that involves changes in the brain. The brain becomes structurally, functionally, and interconnected differently. The evolution of brain activity and its anatomy follows separate paths, causing them to not always align. Independent Component Analysis (ICA), a Blind Source Separation (BSS) method, enables brain parcellation considering an individual's functional patterns. This is advantageous when studying brain function at different stages of life, allowing for a more comprehensive and flexible approach that accounts for age-related differences. This study aims to investigate the relationship between age and functional networks, exploring the differences in the functional parcellations of two different age groups and their networks. We propose a method utilizing group-ICA that identifies functional connectivity patterns to estimate coherent networks. We found variations in the distribution of the age-related networks and the brain portions they covered; some networks in old adults encompassed smaller areas in comparison to the networks in young adults.
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language English
publishDate 2024-12-01
publisher Elsevier
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spelling doaj-art-d6bd204fa46a450dbbdfbeeb38a4d62e2025-08-20T01:58:16ZengElsevierFranklin Open2773-18632024-12-01910017810.1016/j.fraope.2024.100178Insights into brain network dynamics across ages using group-ICA functional parcellationLorena Malinalli López-Medina0Omar Paredes1Sorpresa Lora-Castro2Rebeca Romo-Vázquez3J. Alejandro Morales4Hugo Vélez-Pérez5Biodigital Innovation Lab, CUCEI, University of Guadalajara. Blvd. Marcelino García Barragán No. 1421, Olímpica, 44430 Guadalajara, Jalisco, MexicoBiodigital Innovation Lab, CUCEI, University of Guadalajara. Blvd. Marcelino García Barragán No. 1421, Olímpica, 44430 Guadalajara, Jalisco, MexicoTranslational Bioengineering Department, CUCEI, University of Guadalajara. Blvd. Marcelino García Barragán No. 1421, Olímpica, 44430 Guadalajara, Jalisco, MexicoTranslational Bioengineering Department, CUCEI, University of Guadalajara. Blvd. Marcelino García Barragán No. 1421, Olímpica, 44430 Guadalajara, Jalisco, MexicoBiodigital Innovation Lab, CUCEI, University of Guadalajara. Blvd. Marcelino García Barragán No. 1421, Olímpica, 44430 Guadalajara, Jalisco, MexicoTranslational Bioengineering Department, CUCEI, University of Guadalajara. Blvd. Marcelino García Barragán No. 1421, Olímpica, 44430 Guadalajara, Jalisco, Mexico; Corresponding author.Aging is a natural and inevitable process in human life that involves changes in the brain. The brain becomes structurally, functionally, and interconnected differently. The evolution of brain activity and its anatomy follows separate paths, causing them to not always align. Independent Component Analysis (ICA), a Blind Source Separation (BSS) method, enables brain parcellation considering an individual's functional patterns. This is advantageous when studying brain function at different stages of life, allowing for a more comprehensive and flexible approach that accounts for age-related differences. This study aims to investigate the relationship between age and functional networks, exploring the differences in the functional parcellations of two different age groups and their networks. We propose a method utilizing group-ICA that identifies functional connectivity patterns to estimate coherent networks. We found variations in the distribution of the age-related networks and the brain portions they covered; some networks in old adults encompassed smaller areas in comparison to the networks in young adults.http://www.sciencedirect.com/science/article/pii/S2773186324001087Brain parcellationfMRIFunctional networkIndependent component analysisResting-state
spellingShingle Lorena Malinalli López-Medina
Omar Paredes
Sorpresa Lora-Castro
Rebeca Romo-Vázquez
J. Alejandro Morales
Hugo Vélez-Pérez
Insights into brain network dynamics across ages using group-ICA functional parcellation
Franklin Open
Brain parcellation
fMRI
Functional network
Independent component analysis
Resting-state
title Insights into brain network dynamics across ages using group-ICA functional parcellation
title_full Insights into brain network dynamics across ages using group-ICA functional parcellation
title_fullStr Insights into brain network dynamics across ages using group-ICA functional parcellation
title_full_unstemmed Insights into brain network dynamics across ages using group-ICA functional parcellation
title_short Insights into brain network dynamics across ages using group-ICA functional parcellation
title_sort insights into brain network dynamics across ages using group ica functional parcellation
topic Brain parcellation
fMRI
Functional network
Independent component analysis
Resting-state
url http://www.sciencedirect.com/science/article/pii/S2773186324001087
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