A comparison study between Candida parapsilosis sepsis and Candida albicans sepsis in preterm infants
In this study, we aimed to investigate the clinical characteristics of Candida parapsilosis sepsis in preterm infants. In this retrospective analysis of the clinical data of 11 cases of Candida parapsilosis sepsis and 13 cases of C. albicans sepsis, the two groups were compared for research u...
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| Format: | Article |
| Language: | English |
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Hacettepe University Institute of Child Health
2012-10-01
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| Series: | The Turkish Journal of Pediatrics |
| Online Access: | https://turkjpediatr.org/article/view/1676 |
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| author | Shaodong Hua Jieting Huang Zhixin Wu Zhichun Feng |
| author_facet | Shaodong Hua Jieting Huang Zhixin Wu Zhichun Feng |
| author_sort | Shaodong Hua |
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In this study, we aimed to investigate the clinical characteristics of Candida parapsilosis sepsis in preterm infants. In this retrospective analysis of the clinical data of 11 cases of Candida parapsilosis sepsis and 13 cases of C. albicans sepsis, the two groups were compared for research using one-way analysis of variance (one-way ANOVA), chi2 test, and non-conditional logistic regression analysis. Compared to the C. albicans sepsis group, the C. parapsilosis group demonstrated a significantly lower birth weight (1331.8 +/- 252.41 vs. 1721.2 +/- 589.08) and significantly longer hospital stay (69.909 +/- 20.782 vs. 38.385 +/- 19.923) (t'/t = 2.160, -3.787; p = 0.045, 0.01, respectively); the incidences of retinopathy of prematurity (ROP) (72.7% vs. 30.8%), tienam administration (72.7% vs. 23.1%), pneumothorax, and thoracic closed drainage (27.3% vs. 0) were higher (chi2 = 4.196, 5.916, 4.052; p = 0.041, 0.015, 0.044, respectively). Logistic regression analysis indicated only hospital stay and tienam administration in the regression equation (chi2 = 18.008, p = 0.000). Compared with C. albicans sepsis, an average length hospital stay and administration of tienam are the high-risk factors for C. parapsilosis sepsis. With regard to the other predisposing factors of preterm infant fungal sepsis, there were no differences between the two groups.
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| format | Article |
| id | doaj-art-d6b55068f9974c4eb356190f1d4de3f6 |
| institution | OA Journals |
| issn | 0041-4301 2791-6421 |
| language | English |
| publishDate | 2012-10-01 |
| publisher | Hacettepe University Institute of Child Health |
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| series | The Turkish Journal of Pediatrics |
| spelling | doaj-art-d6b55068f9974c4eb356190f1d4de3f62025-08-20T02:01:53ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212012-10-01545A comparison study between Candida parapsilosis sepsis and Candida albicans sepsis in preterm infantsShaodong Hua0Jieting HuangZhixin WuZhichun FengDepartment of Pediatrics, BaYi Children's Hospital of the General Military Hospital of Beijing PLA, Beijing, PR China. In this study, we aimed to investigate the clinical characteristics of Candida parapsilosis sepsis in preterm infants. In this retrospective analysis of the clinical data of 11 cases of Candida parapsilosis sepsis and 13 cases of C. albicans sepsis, the two groups were compared for research using one-way analysis of variance (one-way ANOVA), chi2 test, and non-conditional logistic regression analysis. Compared to the C. albicans sepsis group, the C. parapsilosis group demonstrated a significantly lower birth weight (1331.8 +/- 252.41 vs. 1721.2 +/- 589.08) and significantly longer hospital stay (69.909 +/- 20.782 vs. 38.385 +/- 19.923) (t'/t = 2.160, -3.787; p = 0.045, 0.01, respectively); the incidences of retinopathy of prematurity (ROP) (72.7% vs. 30.8%), tienam administration (72.7% vs. 23.1%), pneumothorax, and thoracic closed drainage (27.3% vs. 0) were higher (chi2 = 4.196, 5.916, 4.052; p = 0.041, 0.015, 0.044, respectively). Logistic regression analysis indicated only hospital stay and tienam administration in the regression equation (chi2 = 18.008, p = 0.000). Compared with C. albicans sepsis, an average length hospital stay and administration of tienam are the high-risk factors for C. parapsilosis sepsis. With regard to the other predisposing factors of preterm infant fungal sepsis, there were no differences between the two groups. https://turkjpediatr.org/article/view/1676 |
| spellingShingle | Shaodong Hua Jieting Huang Zhixin Wu Zhichun Feng A comparison study between Candida parapsilosis sepsis and Candida albicans sepsis in preterm infants The Turkish Journal of Pediatrics |
| title | A comparison study between Candida parapsilosis sepsis and Candida albicans sepsis in preterm infants |
| title_full | A comparison study between Candida parapsilosis sepsis and Candida albicans sepsis in preterm infants |
| title_fullStr | A comparison study between Candida parapsilosis sepsis and Candida albicans sepsis in preterm infants |
| title_full_unstemmed | A comparison study between Candida parapsilosis sepsis and Candida albicans sepsis in preterm infants |
| title_short | A comparison study between Candida parapsilosis sepsis and Candida albicans sepsis in preterm infants |
| title_sort | comparison study between candida parapsilosis sepsis and candida albicans sepsis in preterm infants |
| url | https://turkjpediatr.org/article/view/1676 |
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