Identification of SCAMP2 as a regulator of NOTCH signaling in cisplatin resistance through a novel prognostic model for bladder cancer

Identification of SCAMP2 as a regulator of NOTCH signaling in cisplatin resistance through a novel prognostic model for bladder cancer

IntroductionBladder cancer remains a major challenge in clinical oncology, particularly due to the development of platinum resistance, which severely impacts patient prognosis. Despite numerous attempts to create effective prognostic models, their clinical applicability has often been limited.Method...

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Bibliographic Details
Main Authors: Longjun Cai, Shaoqi Zhang, Fangfang Zheng, Furong Ji, Jin Wang, Long Shi, Liu Chao, Xiangyu Wang, Jianjun Zhang, Zhiyong Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
cisplatin sensitivity
prognostic model
bladder cancer
SCAMP2
notch pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1573412/full
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