Residual baculovirus in insect cell-derived influenza virus-like particle preparations enhances immunogenicity.
Influenza virus-like particles are currently evaluated in clinical trials as vaccine candidates for influenza viruses. Most commonly they are produced in baculovirus- or mammalian- expression systems. Here we used different vaccination schemes in order to systematically compare virus-like particle p...
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| Main Authors: | Irina Margine, Luis Martinez-Gil, Yi-Ying Chou, Florian Krammer |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2012-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0051559&type=printable |
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