Case Report: Collision tumors of the sellar region: pituitary adenoma and chordoma coexist in the sellar region
Collision tumors are relatively rare and refer to the coexistence of distinct tumors in the same anatomical region, where they invade each other. Sellar collision tumors are especially uncommon. Recent studies suggest that most cases involve the coexistence of pituitary adenomas and craniopharyngiom...
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| Format: | Article |
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Frontiers Media S.A.
2025-06-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2025.1605605/full |
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| author | Shuo Gao Pule Liu Shude Yang Kai Liu Zhiqiang Zhao Yadong Wang Qiang Li Jinqian Dong |
| author_facet | Shuo Gao Pule Liu Shude Yang Kai Liu Zhiqiang Zhao Yadong Wang Qiang Li Jinqian Dong |
| author_sort | Shuo Gao |
| collection | DOAJ |
| description | Collision tumors are relatively rare and refer to the coexistence of distinct tumors in the same anatomical region, where they invade each other. Sellar collision tumors are especially uncommon. Recent studies suggest that most cases involve the coexistence of pituitary adenomas and craniopharyngiomas, whereas collision tumors comprising pituitary adenomas and chordomas are exceedingly rare. To the best of our knowledge, this case represents the fourth reported instance of an intrasellar chordoma coexisting with a pituitary adenoma. This case report presents a 60-year-old male patient with a collision tumor consisting of a sellar chordoma and a pituitary adenoma. Enhanced MRI identified a large space-occupying lesion involving the sellar region, suprasellar area, and third ventricle, suspected to be a soft tissue chordoma. Histopathological examination following endoscopic transnasal surgery confirmed the diagnosis of a sellar chordoma coexisting with a pituitary adenoma. This case offers valuable insights into the clinical manifestations and imaging characteristics of sellar chordoma coexisting with pituitary adenoma, contributing to a better understanding of this rare condition. Furthermore, this article reviews the existing literature, serving as a reference for the diagnosis and management of such conditions. |
| format | Article |
| id | doaj-art-d694a1a163ca4cc490ca6553d27ebcc3 |
| institution | OA Journals |
| issn | 1664-2392 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj-art-d694a1a163ca4cc490ca6553d27ebcc32025-08-20T02:07:24ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922025-06-011610.3389/fendo.2025.16056051605605Case Report: Collision tumors of the sellar region: pituitary adenoma and chordoma coexist in the sellar regionShuo Gao0Pule Liu1Shude Yang2Kai Liu3Zhiqiang Zhao4Yadong Wang5Qiang Li6Jinqian Dong7Department of Neurosurgery, The Second Hospital & Clinical Medical School, Lanzhou University, Gansu, ChinaDepartment of Neurosurgery, The Second Hospital & Clinical Medical School, Lanzhou University, Gansu, ChinaDepartment of Neurosurgery, The Second Hospital & Clinical Medical School, Lanzhou University, Gansu, ChinaDepartment of Neurosurgery, The Second Hospital & Clinical Medical School, Lanzhou University, Gansu, ChinaDepartment of Pathology, The Second Hospital & Clinical Medical School, Lanzhou University, Gansu, ChinaDepartment of Emergency, Qingyang Xifeng District People’s Hospital, Gansu, ChinaDepartment of Neurosurgery, The Second Hospital & Clinical Medical School, Lanzhou University, Gansu, ChinaDepartment of Neurosurgery, The Second Hospital & Clinical Medical School, Lanzhou University, Gansu, ChinaCollision tumors are relatively rare and refer to the coexistence of distinct tumors in the same anatomical region, where they invade each other. Sellar collision tumors are especially uncommon. Recent studies suggest that most cases involve the coexistence of pituitary adenomas and craniopharyngiomas, whereas collision tumors comprising pituitary adenomas and chordomas are exceedingly rare. To the best of our knowledge, this case represents the fourth reported instance of an intrasellar chordoma coexisting with a pituitary adenoma. This case report presents a 60-year-old male patient with a collision tumor consisting of a sellar chordoma and a pituitary adenoma. Enhanced MRI identified a large space-occupying lesion involving the sellar region, suprasellar area, and third ventricle, suspected to be a soft tissue chordoma. Histopathological examination following endoscopic transnasal surgery confirmed the diagnosis of a sellar chordoma coexisting with a pituitary adenoma. This case offers valuable insights into the clinical manifestations and imaging characteristics of sellar chordoma coexisting with pituitary adenoma, contributing to a better understanding of this rare condition. Furthermore, this article reviews the existing literature, serving as a reference for the diagnosis and management of such conditions.https://www.frontiersin.org/articles/10.3389/fendo.2025.1605605/fullcollision tumorschordomapituitary adenomasellar regioncase report |
| spellingShingle | Shuo Gao Pule Liu Shude Yang Kai Liu Zhiqiang Zhao Yadong Wang Qiang Li Jinqian Dong Case Report: Collision tumors of the sellar region: pituitary adenoma and chordoma coexist in the sellar region Frontiers in Endocrinology collision tumors chordoma pituitary adenoma sellar region case report |
| title | Case Report: Collision tumors of the sellar region: pituitary adenoma and chordoma coexist in the sellar region |
| title_full | Case Report: Collision tumors of the sellar region: pituitary adenoma and chordoma coexist in the sellar region |
| title_fullStr | Case Report: Collision tumors of the sellar region: pituitary adenoma and chordoma coexist in the sellar region |
| title_full_unstemmed | Case Report: Collision tumors of the sellar region: pituitary adenoma and chordoma coexist in the sellar region |
| title_short | Case Report: Collision tumors of the sellar region: pituitary adenoma and chordoma coexist in the sellar region |
| title_sort | case report collision tumors of the sellar region pituitary adenoma and chordoma coexist in the sellar region |
| topic | collision tumors chordoma pituitary adenoma sellar region case report |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2025.1605605/full |
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