Association between mitochondrial SIRTs (SIRT3, SIRT4, and SIRT5) and PCOS

Association between mitochondrial SIRTs (SIRT3, SIRT4, and SIRT5) and PCOS

Abstract Polycystic ovary syndrome (PCOS) is a complex endocrine and metabolic disorder with unclear pathogenesis. Increasing evidence suggests that oxidative stress and mitochondrial dysfunction contribute to PCOS development. Sirtuins (SIRTs), especially mitochondrial SIRTs (SIRT3, SIRT4, and SIRT...

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Bibliographic Details
Main Authors: Liying Huang, Xiao Qin, Chun Tian, Shaohua Ling, Xiaoqiong Luo, Bingsheng Huang, Yanlan Ling, Shenwen Zhong, Zhi Li, Li Qin
Format: Article
Language:English
Published: BMC 2025-07-01
Series:European Journal of Medical Research
Subjects:
Polycystic ovary syndrome
SIRT3
SIRT4
SIRT5
Pathogenesis
Online Access:https://doi.org/10.1186/s40001-025-02862-3
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