Supplementation of inactivated influenza vaccine with norovirus P particle-M2e chimeric vaccine enhances protection against heterologous virus challenge in chickens.

Supplementation of inactivated influenza vaccine with norovirus P particle-M2e chimeric vaccine enhances protection against heterologous virus challenge in chickens.

The current inactivated influenza vaccines provide satisfactory protection against homologous viruses but limited cross-protection against antigenically divergent strains. Consequently, there is a need to develop more broadly protective vaccines. The highly conserved extracellular domain of the matr...

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Main Authors: Mohamed Elaish, John M Ngunjiri, Ahmed Ali, Ming Xia, Mahmoud Ibrahim, Hyesun Jang, Jagadish Hiremath, Santosh Dhakal, Yosra A Helmy, Xi Jiang, Gourapura J Renukaradhya, Chang-Won Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0171174&type=printable
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