A review on Actinomycetes distribution, isolation, and their medical applications

Actinomycetes (Actinobacteria) are Gram-positive bacteria that grow in a variety of environments and have a filamentous shape similar to fungi. The actinomycetes distinguish themselves morphologically by forming a layer of hyphae that carry chains of spores. The aim of this study was to update the r...

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Main Authors: Abeer Muazi Alenazi, Yasir Anwar, Salah E.M. Abo-Aba, Noor M. Bataweel
Format: Article
Language:English
Published: ResearchersLinks, Ltd 2023-04-01
Series:Novel Research in Microbiology Journal
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Online Access:https://nrmj.journals.ekb.eg/article_294180_446493c5a599c962e339cc15dc056434.pdf
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author Abeer Muazi Alenazi
Yasir Anwar
Salah E.M. Abo-Aba
Noor M. Bataweel
author_facet Abeer Muazi Alenazi
Yasir Anwar
Salah E.M. Abo-Aba
Noor M. Bataweel
author_sort Abeer Muazi Alenazi
collection DOAJ
description Actinomycetes (Actinobacteria) are Gram-positive bacteria that grow in a variety of environments and have a filamentous shape similar to fungi. The actinomycetes distinguish themselves morphologically by forming a layer of hyphae that carry chains of spores. The aim of this study was to update the recent developments related to the actinomycetes. Streptomyces; as an actinomycete, is known for producing a number of bioactive secondary metabolites, including anti-tumour agents; antibiotics, antifungals, antivirals, anti-hypertension drugs, and immunosuppressives. In order to compete with other microorganisms, including those of the same genera, Streptomyces species produce several secondary metabolites. However, despite the discovery of antibiotics, the infectious diseases remain the second- leading cause of death worldwide. Each year, around 17 million people die from bacterial infections; mainly children and the elderly. In addition to the overuse of antibiotics, a key factor contributing to antibiotic resistance is self-medication, which reduces the lifespan of antibiotics.
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spelling doaj-art-d68ca1c9dce643e7b6971e243ff0e22a2025-08-20T02:54:40ZengResearchersLinks, LtdNovel Research in Microbiology Journal2537-02862537-02942023-04-0121918193110.21608/nrmj.2023.294180A review on Actinomycetes distribution, isolation, and their medical applicationsAbeer Muazi Alenazi0Yasir Anwar1Salah E.M. Abo-Aba2Noor M. Bataweel3Department of Biological sciences, Faculty of science, King Abdulaziz University, Jeddah, Saudi ArabiaDepartment of Biological sciences, Faculty of science, King Abdulaziz University, Jeddah, Saudi ArabiaDepartment of Biological sciences, Faculty of science, King Abdulaziz University, Jeddah, Saudi ArabiaKing Fahd Medical Research center, Jeddah, Saudi ArabiaActinomycetes (Actinobacteria) are Gram-positive bacteria that grow in a variety of environments and have a filamentous shape similar to fungi. The actinomycetes distinguish themselves morphologically by forming a layer of hyphae that carry chains of spores. The aim of this study was to update the recent developments related to the actinomycetes. Streptomyces; as an actinomycete, is known for producing a number of bioactive secondary metabolites, including anti-tumour agents; antibiotics, antifungals, antivirals, anti-hypertension drugs, and immunosuppressives. In order to compete with other microorganisms, including those of the same genera, Streptomyces species produce several secondary metabolites. However, despite the discovery of antibiotics, the infectious diseases remain the second- leading cause of death worldwide. Each year, around 17 million people die from bacterial infections; mainly children and the elderly. In addition to the overuse of antibiotics, a key factor contributing to antibiotic resistance is self-medication, which reduces the lifespan of antibiotics. https://nrmj.journals.ekb.eg/article_294180_446493c5a599c962e339cc15dc056434.pdfstreptomyces spp.methods of isolationdistributionantibacterial activitysecondary metabolitesantibiotics
spellingShingle Abeer Muazi Alenazi
Yasir Anwar
Salah E.M. Abo-Aba
Noor M. Bataweel
A review on Actinomycetes distribution, isolation, and their medical applications
Novel Research in Microbiology Journal
streptomyces spp.
methods of isolation
distribution
antibacterial activity
secondary metabolites
antibiotics
title A review on Actinomycetes distribution, isolation, and their medical applications
title_full A review on Actinomycetes distribution, isolation, and their medical applications
title_fullStr A review on Actinomycetes distribution, isolation, and their medical applications
title_full_unstemmed A review on Actinomycetes distribution, isolation, and their medical applications
title_short A review on Actinomycetes distribution, isolation, and their medical applications
title_sort review on actinomycetes distribution isolation and their medical applications
topic streptomyces spp.
methods of isolation
distribution
antibacterial activity
secondary metabolites
antibiotics
url https://nrmj.journals.ekb.eg/article_294180_446493c5a599c962e339cc15dc056434.pdf
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