Investigation of the effect of thymoquinone and doxorubicin on the EGFR/FOXP3 signaling pathway in OVCAR3 human ovarian adenocarcinoma cells

Investigation of the effect of thymoquinone and doxorubicin on the EGFR/FOXP3 signaling pathway in OVCAR3 human ovarian adenocarcinoma cells

ABSTRACT Purpose: To investigate the cytotoxic and apoptotic effects of the combination of doxorubicin (Dox) and thymoquinone (TQ) on ovarian adenocarcinoma cells (OVCAR3) via the EGFR/FOXP3 signaling pathway. Methods: We used human OVCAR3 and human skin keratinocyte cells (HaCaT). Different conce...

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Bibliographic Details
Main Authors:	İlhan Özdemir, Ayfer Şanli Aktaş, Mehmet Cudi Tuncer
Format:	Article
Language:	English
Published:	Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2025-03-01
Series:	Acta Cirúrgica Brasileira
Subjects:	Ovary Antioxidants Epidermal Growth Factor Receptor Forkhead Box Protein O3 Apoptosis Cell Movement
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502025000100216&lng=en&tlng=en
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