Resection or radiofrequency ablation of colorectal liver metastasis
Background/Aim. Liver resection is the treatment of choice for solitary colorectal liver metastases in suitable candidates. Recently, radiofrequency ablation (RFA) has become a very popular procedure in the treatment of liver metastases. The aim of this study was to compare outcomes in pati...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2014-01-01
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| Series: | Vojnosanitetski Pregled |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2014/0042-84501406542J.pdf |
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| Summary: | Background/Aim. Liver resection is the treatment of choice for solitary
colorectal liver metastases in suitable candidates. Recently, radiofrequency
ablation (RFA) has become a very popular procedure in the treatment of liver
metastases. The aim of this study was to compare outcomes in patients with
solitary colorectal liver metastasis who had been subjected to resection or
ablation. Methods. In this retrospective study we analyzed and compared
patients with solitary colorectal liver metastases treated by resection or
ablation in the University Hospital Centre “Dr Dragiša Mišović” in Belgrade
from January 2002 until December 2009. Results. In this study 94 (67.1%)
patients underwent resection whereas 46 (32.9%) patients underwent RFA. Most
of the resected patients (59.6%) required major hepatectomy. The median
follow-up time was 28.4 months. Tumor ablation was a significant predictor of
the overall survival (p = 0.002; OR 3.75; 95% CI 1.696-8.284). Our study
demonstrated longer disease free-survival in the group of resected patients
compared to the RFA group (37.6 vs 22.3 months, p = 0.073). The median
overall survival was 56.3 months for patients who underwent resection vs 25.1
months for those in the RFA group (p = 0.005). Conclusion. This study shows
that the patients with solitary hepatic colorectal cancer metastases should
be considered for hepatic resection whenever it is feasible, because this
procedure provides superior long-term survival as compared to radiofrequency
ablation. |
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| ISSN: | 0042-8450 |