Exploring the Distribution of ABO and Rhesus Blood Groups among Beta Thalassemia Patients in Punjab, Pakistan: A Cross-Sectional Study
Background: Beta thalassemia is a genetic hematological disorder characterized by impaired or absent hemoglobin synthesis. It is affecting millions around the world, posing them for a lifelong blood transfusion. People have different blood types based on genetically determined antigens that play a...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Faculty of Science, The University of Azad Jammu & Kashmir, Muzaffarabad
2025-06-01
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| Series: | Kashmir Journal of Science |
| Online Access: | https://kjs.org.pk/index.php/kjs/article/view/77 |
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| Summary: | Background: Beta thalassemia is a genetic hematological disorder characterized by impaired or absent hemoglobin synthesis. It is affecting millions around the world, posing them for a lifelong blood transfusion. People have different blood types based on genetically determined antigens that play a vital role in transfusion safety. Blood group antigens show strong correlation with many diseases like Diabetes, immune disorders, cancers etc.
Objectives: We aimed to find out distribution of ABO and Rh blood groups in thalassemic patients. We analyzed the impact of age, gender and caste on distribution of ABO and Rh blood groups.
Methods: This study included 188 thalassemic patients. It was a cross sectional, single centric and observational study. The ABO blood groups were screened by slide hemagglutination method after the permission from the ethics committee and with the consent from the patients.
Results: We observed that thalassemia is more common in blood group B. Gender wise and age wise distribution of thalassemia was in order of B>O>A>AB. Thalassemia was more common in males with Rh +ve blood groups than Rh –ve.
Conclusion: It was found that the most affected blood group with beta thalassemia is B +ve. We conclude that males are more affected with thalassemia major than females. More thalassemic patients were found to be Rh +ve.
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| ISSN: | 2958-7832 |